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Item Mental Health Outcomes during Colorectal Cancer Survivorship: A Review of the Literature(Wiley, 2016-11) Mosher, Catherine E.; Winger, Joseph G.; Given, Barbara A.; Helft, Paul R.; O’Neil, Bert H.; Psychology, School of ScienceObjective This article reviews literature on adults’ mental health outcomes during acute and long-term colorectal cancer (CRC) survivorship. Methods We identified articles that included at least one measure of psychological symptoms or mental quality of life or well-being through a search of databases (CINAHL, MEDLINE, PsycINFO, and PsycARTICLES). Articles were published between January 2004 and April 2015. Results A significant proportion of CRC survivors experience clinically meaningful levels of anxiety and depressive symptoms or reduced mental well-being across the trajectory of the illness. Demographic, medical, and psychosocial predictors of mental health outcomes were identified. However, few studies were theory-driven, and gaps remain in our understanding of risk and protective factors with respect to mental health outcomes, especially during long-term CRC survivorship. Conclusions Theory-driven longitudinal research with larger samples is required to identify subgroups of CRC survivors with different trajectories of psychological adjustment. Such research would assess adjustment as a function of internal resources (e.g., personality, coping) and external resources (e.g., finances, social support) to inform future interventions for CRC survivors.