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Item From sequence to structure, to function, and back again: Integrating knowledge-based approaches with physical intuitions for protein folding, binding, and design(Office of the Vice Chancellor for Research, 2010-04-09) Zhou, YaoqiBy combining physical and knowledge-based approaches, state-of-the-art bioinformatics tools are developed for protein structure prediction, function prediction (DNA binding) and structurebased protein and ligand design.