Browsing by Subject "movement disorders"

Now showing 1 - 2 of 2
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    Movement Disorders and Neurometabolic Diseases
    (Elsevier, 2018) Christensen, Celanie K.; Walsh, Laurence; Neurology, School of Medicine
    Many inherited metabolic disorders cause movement disorders in children. This review focuses on chorea, dystonia, myoclonus, tremor, and parkinsonism. Broad categories commonly responsible for pediatric movement disorders include mitochondrial disorders, organic acidemias, mineral metabolism and transport disorders, neurotransmitter diseases, purine metabolism disorders, lipid storage disorders, and disorders of creatine metabolism. Each movement disorder can be caused by many different inherited metabolic disorders and several of the inherited metabolic disorders can cause multiple movement abnormalities. Dietary modifications, medications, and increasingly specific therapy can improve outcomes in children with movement disorders caused by metabolic disorders. Recognition and characterization of secondary movement disorders in children facilitate management of the abnormal movements and diagnosis, and possible treatment, of an underlying metabolic disorder.
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    Psychiatric Treatment and Management of Psychiatric Comorbidities of Movement Disorders
    (Elsevier, 2017) Walsh, Kelda Harris; Soe, Katherine; Sarawgi, Shivali; Psychiatry, School of Medicine
    Pediatric movement disorders may present with psychiatric symptoms at many points during the course of the disease. For the relatively common pediatric movement disorder, Tourette syndrome, psychiatric comorbidities are well-described and treatment is well-studied. Treating these comorbidities may be more effective than treating the movements themselves. For more uncommon movement disorders, such as juvenile-onset Huntington disease, treatment of psychiatric comorbidities is not well-characterized, and best practice recommendations are not available. For the least common movement disorders, such as childhood neurodegeneration with brain iron accumulation, psychiatric features may be nonspecific, so that underlying diagnosis may be apparent only after recognition of other symptoms. However, psychiatric medication, psychotherapy, and psychosocial support for these disorders may prove helpful to many children and adolescents.