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Browsing by Subject "molar hypomineralization"
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Item Early Lead Exposure Associated with Molar Hypomineralization(American Academy of Pediatric Dentistry, 2023-09) Tagelsir, Ahmed A.; Hector, Emily C.; Urena-Cirett, Jose Luis; Mercado-Garcia, Adriana; Cantoral, Alejandra; Hu, Howard; Peterson, Karen E.; Tellez-Rojo, Martha M.; Martinez-Mier, Esperanza A.; Dental Public Health and Dental Informatics, School of DentistryPurpose: The purpose of this study was to determine the association between prenatal and early life exposure to lead and the presence of molar hypomineralization (MH) in a group of Mexican children. Methods: A subset of participants of the Early Life Exposure in Mexico to Environmental Toxicants (ELEMENTS) cohort study was examined for the presence of molar hypomineralization using European Academy of Pedi- atric Dentistry (EAPD) criteria. Prenatal lead exposure was assessed by K-ray fluorescence measurements of patella and tibia lead and by maternal blood lead levels by trimester and averaged over trimesters. Postnatal exposure was assessed by levels of maternal blood lead at delivery and child blood lead at 12 and 24 months. Results: A subset of 506 subjects from the ELEMENT cohorts (nine to 18 years old) were examined for MH; 87 subjects (17.2 percent) had MH. Maternal blood lead levels in the third trimester (odds ratio [OR] equals 1.08; 95 percent confidence interval [95% CI] equals 1.02 to 1.15) and averaged over three trimesters (OR equals 1.10; 95% CI equals 1.02 to 1.19) were significantly associated with MH status. None of the maternal bone lead or the child's blood lead parameters was significantly associated with the presence of MH (P>0.05). Conclusions: This study documents a significant association between prenatal lead exposure especially in late pregnancy and the odds of molar hypomineralization.Item U.S. Pediatric Dentists’ Perception of Molar Incisor Hypomineralization(AAPD, 2018) Tagelsir, Azza; Dean, Jeffrey A.; Eckert, George J.; Martinez Mier, Esperanza A.; Pediatric Dentistry, School of DentistryPurpose: The purpose of this survey-based study was to target U.S. pediatric dentists in the Midwest region to determine their knowledge, perceptions, and clinical management strategies of molar incisor hypomineralization (MIH). Methods: After obtaining appropriate authorizations, all pediatric dentists identified by the American Academy of Pediatric Dentistry's 2016 to 2017 membership directory in the 12 Midwest states were invited to take part in the study. The questionnaire, adopted from previous studies, incorporated information of the participants' demographics and educational/clinical backgrounds and MIH-focused questions. Descriptive statistics and chi-square tests were used for analysis. An alpha level less than 0.05 was considered statistically significant. Results: A total of 251 out of 975 surveys were completed (26 percent). Nearly all participants were familiar with MIH. The majority reported the MIH prevalence to be less than 10 percent in their clinical practice (62 percent). Most respondents were either very confident (65 percent) or confident (34 percent) when diagnosing teeth with MIH. The most cited clinical challenge in managing MIH teeth was "long-term success of restorations" (79 percent). When analyzed individually, responses differed significantly for different demographics and educational characteristics of the respondents (P<0.05). Conclusion: MIH is generally well acknowledged by U.S. Midwest pediatric dentists, with differences related to their perceptions of the condition's prevalence as well as clinical and restorative management challenges.