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Item Formula Mixing Knowledge of Pediatric Residents at a Quaternary Care Center(2022-04-28) Andrewski, ErikPediatric residents receive a paucity of training in regards to best practices for formula mixing and storage leading to decreased comfort and discussion regarding formula at well-child checks. 18% of infants are never offered breast milk and over half of infants are receiving formula by 3 months of age. A large majority of parents report they received no guidance about formula mixing from healthcare providers and may be afraid to ask questions related to formula due to a significant culture of “formula shaming”. Complications of improper mixing include electrolyte abnormalities, hypo or hyperglycemia and failure to thrive. Resident knowledge regarding formula best practices was assessed and found to be deficient for both storage and mixing. A self-paced educational module was created to help residents improve their knowledge of infant formula use.Item Mixed Message on Formula Mixing(AAP, 2019-06) Wilkinson, Tracey A.; Scott, Emily K.; Carroll, Aaron E.; Pediatrics, School of MedicineItem Sources, Production, and Clinical Treatments of Milk Fat Globule Membrane for Infant Nutrition and Well-Being(MDPI, 2020-05-30) Fontecha, Javier; Brink, Lauren; Wu, Steven; Pouliot, Yves; Visioli, Francesco; Jiménez-Flores, Rafael; Pediatrics, School of MedicineResearch on milk fat globule membrane (MFGM) is gaining traction. The interest is two-fold; on the one hand, it is a unique trilayer structure with specific secretory function. On the other hand, it is the basis for ingredients with the presence of phospho- and sphingolipids and glycoproteins, which are being used as food ingredients with valuable functionality, in particular, for use as a supplement in infant nutrition. This last application is at the center of this Review, which aims to contribute to understanding MFGM’s function in the proper development of immunity, cognition, and intestinal trophism, in addition to other potential effects such as prevention of diseases including cardiovascular disease, impaired bone turnover and inflammation, skin conditions, and infections as well as age-associated cognitive decline and muscle loss. The phospholipid composition of MFGM from bovine milk is quite like human milk and, although there are some differences due to dairy processing, these do not result in a chemical change. The MFGM ingredients, as used to improve the formulation in different clinical studies, have indeed increased the presence of phospholipids, sphingolipids, glycolipids, and glycoproteins with the resulting benefits of different outcomes (especially immune and cognitive outcomes) with no reported adverse effects. Nevertheless, the precise mechanism(s) of action of MFGM remain to be elucidated and further basic investigation is warranted.