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Item Re-infection with different SARS-CoV-2 clade and prolonged viral shedding in a patient with hematopoietic stem cell transplantation: SARS-CoV-2 Re-infection with different clade(Elsevier, 2021-07-18) Alshukairi, Abeer N.; El-Kafrawy, Sherif A.; Dada, Ashraf; Yasir, Mohamed; Yamani, Amani H.; Saeedi, Mohammed F.; Aljohaney, Ahmed; AlJohani, Naif I.; Bahaudden, Husam A.; Alam, Intikhab; Gojobori, Takashi; Radovanovic, Aleksandar; Alandijany, Thamir A.; Othman, Norah A.; Alsubhi, Tagreed L.; Hassan, Ahmed M.; Tolah, Ahmed M.; Al-Tawfiq, Jaffar A.; Zumla, Alimuddin; Azhar, Esam I.; Medicine, School of MedicineImmunocompromised patients who have SARS-CoV-2 infection pose many clinical and public health challenges. We describe a patient with hematopoietic stem cell transplantation and lymphoma with protracted illness requiring 3 consecutive hospital admissions. Whole genome sequencing confirmed two different SARS-CoV-2 clades. Clinical management issues, and unanswered questions arising are discussed.