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Item DESIGNING THE ULTIMATE VIDEO GAMING ENVIRONMENT: THESIS PORTION OF THE MOUNT OLIVE MISSIONARY BAPTIST SHELTER RENOVATION CAPSTONE PROJECT(Office of the Vice Chancellor for Research, 2012-04-13) Rhodes, Jordan A.; Hovde, Marjorie Rush; Nickolson, Darrell D.When the client mentioned that he wanted the space adjoining the gam-ing space to appeal to college age adults, the importance of acoustical sepa-ration was placed into the forefront of my mind. Additionally, much has been said in the media about the negative health benefits of extended video gam-ing play. This thesis project will seek to uncover tangle characteristics of an enjoyable and healthy video gaming environment that can then be incorpo-rated into the overall design of the video gaming den. There is a particular focus on seating and acoustics. The space will need to preserve the experi-ence for the gamers and observers as well as preserve the peace for every-one else without the isolation that usually accompanies a game room. Seat-ing should facilitate a healthy gaming experience as well as add to the im-mersive quality of the gaming environment. In conjunction with the capstone course, this thesis project completes the interior design senior experience required for graduation.Item DHA Alters Raft-like Membrane Domains as Revealed by Solid State 2H NMR Spectroscopy(Office of the Vice Chancellor for Research, 2015-04-17) Kinnun, Jacob J.; Williams, Justin A.; Stillwell, William; Bittman, Robert; Shaikh, Saame Raza; Wassall, Stephen R.Dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs), such as docosahexaenoic acid (DHA, 22:6), are correlated with the prevention of neurological and autoimmune disorders in humans. These fatty acids must be obtained from the diet, such as oil fish or fish oil supplements, as they cannot be generated within the human body. The origin of the health benefits at the molecular level is still under question. A membrane-mediated mechanism in which n-3 PUFAs are incorporated into phospholipids and modulate molecular organization is one possibility. Cellular membranes are inhomogeneous where structurally diverse lipids can exist in separate domains. Regions rich in sphingomyelin (SM) and cholesterol, commonly called lipid rafts, contain important signaling proteins. In a recent solid-state 2H nuclear magnetic resonance (2H NMR) study of a model membrane composed of 1-[2H31] palmitoyl-2-docosahexaenoyl-phosphatidylcholine (PDPC-d31), a deuterated analog of a DHA-containing phospholipid, in mixtures with SM and cholesterol, we discovered that DHA could significantly enter raft-like domains. How DHA affects the molecular organization within the raft-like domains is addressed here by observing PSM-d31, an analog of SM with a perdeuterated N-palmitoyl chain. The 2H NMR spectra for PSM-d31, in mixtures with PDPC and cholesterol, exhibit two spectral components, a larger more ordered component that we attribute to raft-like domains and a smaller less ordered component that we attribute to non-raft-like domains. On average, the order of PSM-d31 is reduced and, thus, disordering of PSM-d31 by PDPC is indicated. Our observations confirm that DHA can infiltrate rafts and affect molecular organization, which has implications for the signaling of raft and non-raft proteins. Furthermore, these results are consistent with in vivo studies showing that DHA infiltrates rafts.