Browsing by Subject "headache"

Now showing 1 - 3 of 3
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    Renal Transplant at MTRH
    (Association of Kenya Physicians, 2007) Owiti, M. O. G.; Association of Kenya Physicians Scientific Conference (11th : Mar. 2007 : Eldoret, Kenya)
    J.A. 48 yrs male - Diabetic since July 1997, on insulin. Crf & high Bp-2004.urea=57.3, crt=1040. Lt kid-7.27x3.62, rt kid8.51x3.34cm, loss of cmd. Haemodialysis x2 wkly till last two wksx3. While on treatment Bp=150/100, pulse78/min. on Adalat 20mg b.d,lasix 80mg od, captopril 25mg b.d,ca-sandoz i.o.d, recormon 2000i.u x2wkly, venofer 100 wkly, ranitidine150 mgo.d. N.C. 17 yrs female - Facial puff, head ache,oliguria, epigastric and bil loin Painsx3/52. 03.08.2004. Post herbal use. Abortion –pph, 07.06.04, post abortal psychosis. Bp220/110mmhg, hb=7.6g/dl, Op=600mls, ip=1.5l.
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    Sensitization of the Trigeminovascular System following Environmental Irritant Exposure
    (Sage, 2015-11) Kunkler, Phillip Edward; Zhang, LuJuan; Pellman, Jessica Joan; Oxford, Gerry Stephen; Hurley, Joyce Harts; Department of Biochemistry and Molecular Biology, IU School of Medicine
    Background Air pollution is linked to increased emergency room visits for headache, and migraine patients frequently cite chemicals or odors as headache triggers, but the association between air pollutants and headache is not well understood. We previously reported that nasal administration of environmental irritants acutely increases meningeal blood flow via a TRPA1-dependent mechanism involving the trigeminovascular system. Here, we examine whether chronic environmental irritant exposure sensitizes the trigeminovascular system. Methods Male rats were exposed to acrolein, a TRPA1 agonist, or room air by inhalation for four days prior to meningeal blood flow measurements. Some animals were injected daily with a TRPA1 antagonist, AP-18, or vehicle prior to inhalation exposure. Trigeminal ganglia were isolated following blood flow measurements for immunocytochemistry and/or qPCR determination of TRPV1, TRPA1 and CGRP levels. Results Acrolein inhalation exposure potentiated blood flow responses both to TRPA1 and TRPV1 agonists compared to room air. Acrolein exposure did not alter TRPV1 or TRPA1 mRNA levels or TRPV1 or CGRP immunoreactive cell counts in the trigeminal ganglion. Acrolein sensitization of trigeminovascular responses to a TRPA1 agonist was attenuated by pre-treatment with AP-18. Interpretation These results suggest trigeminovascular sensitization as a mechanism for enhanced headache susceptibility after chemical exposure.
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    The TMD-7 as a Brief Measure for Assessing Temporomandibular Disorder
    (Thieme, 2022) Koufos, Emily B.; Avila, Harold C.; Eckert, George; Stewart, Kelton T.; Kroenke, Kurt; Turkkahraman, Hakan; Orthodontics and Oral Facial Genetics, School of Dentistry
    Objectives The aim of this cross-sectional prospective study was to determine the internal consistency of the TMD-7, and compare prevalence of TMD symptoms in an adult population. Materials and Methods Upon presenting to the orthodontic screening appointment, a total of 440 subjects (316 females and 124 males) were asked to complete the TMD-7 questionnaire. A total of 108 of the participants were later excluded from the study either due to the duplicate or missing responses. The final sample consisted of data from 332 participants (232 females and 100 males), aged between 18 and 64 (mean age: 42.9 ± 9.0) years. Statistical Analysis Cronbach's α statistics were calculated to assess internal consistency. Comparisons between genders, among age categories, and between subjects with versus without prior orthodontic treatment were performed using Wilcoxon ranks sum and Kruskal–Wallis tests. Comparisons for differences in the individual TMD-7 item ratings were performed using Mantel–Haenszel chi-square tests for ordered categorical responses. Results The calculated Cronbach's α for TMD-7 scale was 0.77. No statistically significant differences were found in the TMD-7 scale score or the individual TMD-7 item ratings between age categories (p = 0.993). Females had significantly higher TMD-7 scale score and higher ratings for headache, pain in jaw, pain in neck, pain in forehead, difficulty opening mouth, and difficulty while eating (p < 0.05). No statistically significant differences were found in the TMD-7 scale score or the individual TMD-7 item ratings between subjects with versus without previous orthodontic treatment (p = 0.075). Conclusion The TMD-7 tool has good internal consistency and can be used reliably for assessment of TMD symptoms in adults. The use of this tool revealed no significant differences between age groups or between subjects with or without previous orthodontic treatment. However, a significant female gender predisposition for TMD symptoms in the adulthood was determined.