Browsing by Subject "discriminant analysis"

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    Letter to the Editor: Metacarpophalangeal Pattern Profile Analysis in Sotos Syndrome: An Update
    (Wiley, 1986-08) Butler, Merlin G.; Meaney, F. John; Medical and Molecular Genetics, School of Medicine
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    Metacarpophalangeal Pattern Profile Analysis in Sotos Syndrome
    (Wiley, 1985-04) Butler, Merlin G.; Meaney, F. John; Kittur, Smita; Hersh, Joseph H.; Hornstein, Lusia; Medical and Molecular Genetics, School of Medicine
    The metacarpophalangeal pattern profile (MCPP) was analyzed on 16 Sotos syndrome patients. A mean Sotos syndrome profile was produced. Correlation studies confirm clinical homogeneity of Sotos syndrome individuals. Discriminant analysis of Sotos syndrome patients and normal individuals produces a function of two MCPP variables and age, which may provide a useful tool for diagnosis.
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    Metacarpophalangeal Pattern Profile Analysis in Sotos Syndrome: A Follow-up Report on 34 Subjects
    (Wiley, 1988-01) Butler, Merlin G.; Dijkstra, Piet F.; Meaney, F. John; Gale, David D.; Medical and Molecular Genetics, School of Medicine
    Metacarpophalangeal pattern profile (MCPP) was determined on 34 Sotos syndrome individuals and compared with previous MCPP studies. The mean hand profile contained a major peak in the proximal phalangeal area and a smaller peak in the metacarpal area, while the distal hand bones were relatively short. There appear to be three recognized hand profiles in Sotos syndrome, which suggests heterogeneity of the syndrome, although correlation studies indicate clinical homogeneity of individuals in the younger age groups. Discriminant analysis of Sotos syndrome versus control subjects produced a function of two MCPP variables, plus age, which may be applied as another diagnostic tool.