Browsing by Subject "confirmatory factor analysis"

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    Confirmatory test of two factors and four subtypes of bipolar disorder based on lifetime psychiatric comorbidity
    (Cambridge, 2015-07) Monahan, Patrick O.; Stump, Timothy; Coryell, William H.; Harezlak, Jaroslaw; Marcoulides, George A.; Liu, Hai; Steeger, Christine M.; Mitchell, Philip B.; Wilcox, Holly C.; Hulvershorn, Leslie A.; Glowinski, Anne L.; Iyer-Eimerbrink, Priya Anapurna; McInnis, Melvin; Nurnberger, John I. Jr.; Department of Biostatistics, IU School of Medicine
    Background The first aim was to use confirmatory factor analysis (CFA) to test a hypothesis that two factors (internalizing and externalizing) account for lifetime co-morbid DSM-IV diagnoses among adults with bipolar I (BPI) disorder. The second aim was to use confirmatory latent class analysis (CLCA) to test the hypothesis that four clinical subtypes are detectible: pure BPI; BPI plus internalizing disorders only; BPI plus externalizing disorders only; and BPI plus internalizing and externalizing disorders. Method A cohort of 699 multiplex BPI families was studied, ascertained and assessed (1998–2003) by the National Institute of Mental Health Genetics Initiative Bipolar Consortium: 1156 with BPI disorder (504 adult probands; 594 first-degree relatives; and 58 more distant relatives) and 563 first-degree relatives without BPI. Best-estimate consensus DSM-IV diagnoses were based on structured interviews, family history and medical records. MPLUS software was used for CFA and CLCA. Results The two-factor CFA model fit the data very well, and could not be improved by adding or removing paths. The four-class CLCA model fit better than exploratory LCA models or post-hoc-modified CLCA models. The two factors and four classes were associated with distinctive clinical course and severity variables, adjusted for proband gender. Co-morbidity, especially more than one internalizing and/or externalizing disorder, was associated with a more severe and complicated course of illness. The four classes demonstrated significant familial aggregation, adjusted for gender and age of relatives. Conclusions The BPI two-factor and four-cluster hypotheses demonstrated substantial confirmatory support. These models may be useful for subtyping BPI disorders, predicting course of illness and refining the phenotype in genetic studies.
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    Development and preliminary validation of the romantic relationship functioning scale
    (2014) Bonfils, Kelsey A.; Salyers, Michelle P.; Minor, Kyle S.; McGrew, John H., 1953-; Grahame, Nicholas J.
    Background: Research has repeatedly shown that individuals with severe mental illness desire interpersonal and romantic relationships and that social support (including spousal relationships) is beneficial. In addition, social deficits in mental disorders can often get in the way of developing fulfilling relationships. However, there is little currently available to help clinicians and researchers assess romantic relationship functioning in those with mental illness. The aim of this pilot study was to examine reliability and validity of a new measure of functioning in romantic relationships, the Romantic Relationship Functioning Scale (RRFS). Method: The RRFS was constructed based on theory proposed by Redmond, Larkin, and Harrop (2010). In an analog study, we tested the measure in a sample of college students (N=387), examining reliability, stability over time, factor structure, and relationships with measures of psychopathology and related measures of social functioning to assess convergent validity. Results: The RRFS exhibited a hierarchical four-factor structure, supporting the use of a total score. Although subscales were supported in the factor analysis, other psychometric evidence was weaker, and the use of a total score is advocated. Internal consistency and test-retest reliability were acceptable for the total scale (>.8). The RRFS had moderate to large correlations in the expected direction with all psychopathology measures. In predictive models, overall mental health, social functioning, and fewer interpersonal difficulties predicted higher romantic relationship functioning. Conclusions: The RRFS total score shows preliminary evidence of reliability and validity. The RRFS has potential to be of use in treatment centers for undergraduates and for individuals with diagnosed mental disorders. Future research should further investigate the RRFS subscales and the measure’s performance in clinical samples.
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    Measurement Invariance and Differential Relationship to Substance Use of the Short UPPS-P Impulsive Behavior Scale Across Racial Groups
    (Sage, 2023-10) Liu, Melissa; Wu, Wei; Zapolski, Tamika; Cyders, Melissa A.; Psychology, School of Science
    The Short UPPS-P Impulsive Behavior (SUPPS-P) scale assesses impulsive traits; however, its use among racial/ethnic minorities needs further testing. The aims of this study are to (a) test the measurement invariance of the SUPPS-P scale between White and racial/ethnic minority groups and (b) determine whether impulsive personality traits differentially relate to substance use outcomes across these groups. Participants were 1,301 young adults and recruited through a large public university or Amazon’s Mechanical Turk. Multigroup confirmatory factor analysis concluded strong measurement invariance for Black, Asian American, and Hispanic/Latino groups, each compared with a White group. Most relationships between SUPPS-P traits and substance use did not differ across the groups compared, although two differences emerged with alcohol use. The SUPPS-P can validly and reliably measure impulsive traits in Black, Hispanic/Latino, and Asian American young to middle adults. Previous findings on risk patterns with the SUPPS-P likely generalize to these groups.