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Item Pilot clinical study to assess caries lesion activity using quantitative light-induced fluorescence during dehydration(SPIE, 2017-03) Ando, Masatoshi; Ferreira-Zandoná, Andrea G.; Eckert, George J.; Zero, Domenick T.; Stookey, George K.; Cariology, Operative Dentistry and Dental Public Health, School of DentistryThis study aimed to evaluate the ability of quantitative light-induced fluorescence (QLF) to assess caries lesion activity using visual examination (VE) as the gold standard. Twenty-four visible white spot lesions on buccal surfaces were examined from 23 children, ages 9 to 14 years. At baseline, the surface was hydrated with water, and thereafter, it was dehydrated with continuous compressed air during image acquisition. QLF images were acquired at 0 (baseline), 5, and 15 s. QLF variables [ QLF V : fluorescence loss ( Δ F ), lesion size (S), Δ Q : Δ F × S ] was recorded. Changes-in- QLF V per second ( Δ QLF V ) were determined: Δ QLF V = ( QLF VN − QLF V Baseline ) / N , where N indicates dehydration time. One experienced dentist conducted VE independently using a dental unit’s light, compressed air, and explorer.