Browsing by Subject "Therapeutic endoscopy"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Item
    A clear approach: Hemostatic gel as a novel adjunct for pediatric upper gastrointestinal bleeding
    (Wolters Kluwer, 2025-02-03) Plott, Natalia; Rougraff, Audra; Bose, Paroma; Tolliver, Kyla M.; Waseem, Shamaila; Hoskins, Brett J.; Pediatrics, School of Medicine
    Pediatric upper gastrointestinal bleeding (UGIB) is a significant clinical concern, with a mortality rate of approximately 2%. Endoscopic management of UGIB in children includes various techniques such as injections, mechanical devices, thermal therapies, and topical agents. PuraStat®, a clear hemostatic gel, has been used in adults to create a physical barrier for hemostasis without obscuring the endoscopic view. However, its use in pediatric UGIB has not been well-documented. A review of four pediatric cases where PuraStat® was used to treat UGIB showed that it was applied as an adjunct to other hemostatic methods like clip placement or epinephrine injections, and in one case, as monotherapy for a large duodenal ulcer/site of recently contained perforation. The gel was easy to use, appeared to be beneficial, and was well-tolerated in this small cohort, although conclusions regarding its safety and efficacy are limited by the sample size.