Browsing by Subject "Sensitivity to change"

Now showing 1 - 2 of 2
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    Longitudinal Evaluation of the HABC Monitor Among Trauma Survivors
    (Dove Press, 2025-03-04) Alhader, Abdelfattah; Perkins, Anthony; Monahan, Patrick O.; Zarzaur, Ben L.; Barboi, Cristina; Boustani, Malaz A.; Medicine, School of Medicine
    Purpose: To examine the sensitivity to change of the Healthy Aging Brain Care Monitor (HABC-M) through a longitudinal analytical comparison with reference standards. Patients and methods: We used longitudinal data from 120 participants in a multicenter randomized controlled trial evaluating the effectiveness of the Trauma Medical Home (TMH). We used the following reference standards: The depression and anxiety subdomains of the Hospital Anxiety and Depression Scale (HADS), the Patient-Reported Outcomes Measurement Information System Sleep Disturbance Short Form 4a (PROMIS-SF), and the Pain, Enjoyment of Life, and General Activity Scale (PEG). We assessed sensitivity to change using three longitudinal comparative analytical methods. The correlation of the HABC-M score with reference standards' scores over time, the correlation of changes in the HABC-M score with changes in reference standards' scores, and a longitudinal analysis to compare changes in the HABC-M against reference standards' known change categories. Results: Throughout the six-month period, the HABC-M exhibited moderate to high correlations with the HADS (r = 0.66, p<0.001 for the depression subdomain and r = 0.42, p<0.001 for the anxiety subdomain), the PROMIS-SF (r = 0.57, p<0.001), and the PEG (r = 0.47, p<0.001). The changes in HABC-M significantly correlated with changes in reference standards at various time points. HABC-M scores were significantly different across known change categories established by the four reference standards, with standardized response mean (SRM) values ranging from 1.08 to 1.44. Conclusion: The HABC-M is capable of monitoring the recovery of older trauma survivors.
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    Responsiveness of PROMIS and Patient Health Questionnaire (PHQ) Depression Scales in three clinical trials
    (BMC, 2021-02-02) Kroenke, Kurt; Stump, Timothy E.; Chen, Chen X.; Kean, Jacob; Damush, Teresa M.; Bair, Matthew J.; Krebs, Erin E.; Monahan, Patrick O.
    The PROMIS depression scales are reliable and valid measures that have extensive normative data in general population samples. However, less is known about how responsive they are to detect change in clinical settings and how their responsiveness compares to legacy measures. The purpose of this study was to assess and compare the responsiveness of the PROMIS and Patient Health Questionnaire (PHQ) depression scales in three separate samples.