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Item A history of the Ronald McDonald House of Indiana, 1980-2004(2012) Mize, Christopher S.; Scarpino, Philip V.; Dichtl, John R., 1965-; Morgan, Anita A.On October 18, 1982, the Ronald McDonald House of Indiana (RMHI) opened near downtown Indianapolis on the campus of Indiana University Purdue University at Indianapolis (IUPUI), located within walking distance of the prestigious Riley Children's Hospital. The Ronald McDonald House (RMH) concept represented an almost perfect intersection between philanthropy and families in need. Creating the RMHI offered the opportunity for individuals, corporations, and benevolent organizations to come together and build a "home-away-from-home" for the families of sick children. When the RMH idea arrived in Indianapolis in the late 1970s, a group of collaborators representing the McDonald's corporation and restaurant owners, Riley Hospital, IUPUI, and the Indianapolis community banded together to make it a reality. On October 18, 1982, after nearly three years planning, fundraising, and construction, the RMHI's advocates and their supporters celebrated the successful opening of Indiana's only RMH. After this momentous occasion, the RMHI's board of directors and their community and corporate partners worked throughout the 1980s and 1990s to sustain, operate, and expand the home they created for the families of seriously ill children receiving treatment at Riley.Item James Whitcomb Riley Hospital for Children: 1924-2024(Ruth Lilly Medical Library, 2024-09-11) Schreiner, Richard L.Presentation slides for lecture delivered by Richard L. Schreiner, MD (Edwin L. Gresham Professor Emeritus of Pediatrics, Indiana University School of Medicine; retired Chair of Pediatrics and Physician-in-Chief, Riley Hospital for Children) on September 11, 2024. In celebration of Riley Hospital for Children’s centennial anniversary, this talk examines the hospital’s one-hundred year history, from the death of its namesake, Indiana poet James Whitcomb Riley, to the establishment of the hospital and the people who made it possible. Important figures, accomplishments, and details about the hospital’s dramatic growth from the 1920s through the present are discussed. Presentation recording available online: https://purl.dlib.indiana.edu/iudl/media/j92g25g53cItem Predictors of Disease Severity in Children at Riley Hospital with Multisystem Inflammatory Syndrome in Children (MIS-C)(2021-07-30) Collins, Angela J.; Rao, Megana; Khaitan, Alka K.; Bhumbra, Samina S.AUTHORS: Angela J. Collins, MPH, BS(1); Megana Rao, BS(1); Alka K. Khaitan, MD(2); Samina S. Bhumbra, MD(2) AFFILIATIONS: (1) Indiana University School of Medicine. (2) Ryan White Center for Pediatric Infectious Disease and Global Health, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana. ABSTRACT: BACKGROUND & OBJECTIVE: Multisystem Inflammatory Syndrome in Children (MIS-C) is a novel condition temporally associated post-SARS-CoV-2-infection. The associated inflammation injures various organs (mainly cardiac and gastrointestinal) and can cause ventricular dysfunction and/or coronary aneurysms, potentially leading to death. This project assessed how lab trends may predict disease outcomes of MIS-C patients at Riley Hospital for Children (RHC). METHODS: Five lab values (intake procalcitonin, platelet count nadir, absolute lymphocyte count nadir, sodium nadir, troponin-I peak, CRP peak) were assessed as potential predictors of MIS-C severity. Patient demographics (age, sex, race, ethnicity), prior medical history (chronic conditions, obesity), and clinical presentation (days of fever prior to admission) were also assessed as potential predictors of MIS-C severity and lab peaks/nadirs. Indicators of MIS-C severity included PICU admission, length of hospital stay, left ventricular ejection fraction (EF), and abnormal coronary artery findings on echocardiogram. Chi-Square, ANOVA, linear regression, and logistic regression models were completed in SAS9.4 to assess for correlation (α=0.05). RESULTS: 66 MIS-C patients, aged 9 months to 18 years (mean=8.7 years), were admitted to RHC May 2020-April 2021. 61% were male (n=41). All patients presented with fever. Average length of stay at RHC was 5.9 days. 47% (n=31) were admitted directly to the PICU and 15% (n=10) were transferred to the PICU during their hospital course. Race predicted sodium nadir (p=0.0363), ethnicity predicted intake procalcitonin (p=0.0007), and obesity predicted CRP peak (p=0.0055). Age predicted abnormal EF (p=0.0206) and abnormal coronary outcome on echocardiogram (p=0.0365). Sex and obesity also predicted abnormal coronary outcome on echocardiogram (p=0.0182 and p=0.0478, respectively). Troponin-I peak predicted abnormal EF (p=0.0035) and CRP peak predicted days of hospital stay (p=0.0096). CONCLUSION & IMPACT: CRP peak is predictive of days of hospital stay and may inform hospital course. Analysis of additional lab values may reveal additional predictors of disease severity to inform clinical care.