Browsing by Subject "Prostate biopsy guidance"

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    Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography
    (Optical Society of America, 2019-02-22) Bungart, Brittani; Cao, Yingchun; Yang-Tran, Tiffany; Gorsky, Sean; Lan, Lu; Roblyer, Darren; Koch, Michael O.; Cheng, Liang; Masterson, Timothy; Cheng, Ji-Xin; Department of Medicine, IU School of Medicine
    Current diagnosis of prostate cancer relies on histological analysis of tissue samples acquired by biopsy, which could benefit from real-time identification of suspicious lesions. Photoacoustic tomography has the potential to provide real-time targets for prostate biopsy guidance with chemical selectivity, but light delivered from the rectal cavity has been unable to penetrate to the anterior prostate. To overcome this barrier, a urethral device with cylindrical illumination is developed for whole-prostate imaging, and its performance as a function of angular light coupling is evaluated with a prostate-mimicking phantom.