Browsing by Subject "Primary cutaneous lymphoma"
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Item Primary cutaneous peripheral T-cell lymphoma, not otherwise specified with mammalian target of rapamycin mutation: A novel finding for targeted treatment(Elsevier, 2020-12) De la Sancha, Carlo; Burgin, Callie; Warren, Simon; Hoffmann, Kristin; Davé, Utpal; Nassiri, Mehdi; Pathology and Laboratory Medicine, School of MedicinePrimary cutaneous peripheral T-cell lymphoma, not otherwise specified (pcPTCL-NOS) is a rare, progressive, and often fatal disease with no specific treatment regimen that presents as rapidly enlarging plaques or nodules. Here, we present a case of progressive pcPTCL-NOS with mammalian target of rapamycin (mTOR) mutation and variable T-cell antigen expression. mTOR mutation in pcPTCL-NOS may represent a new therapeutic target.