Browsing by Subject "Postoperative outcomes"

Now showing 1 - 4 of 4
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    Clinical trends and effects on quality metrics for surgical gastroesophageal cancer care
    (AME Publishing Company, 2018-07-19) Schwarz, Roderich E.; Surgery, School of Medicine
    Background: Surgical therapy of mid-stage gastric cancer (GC) and other neoplastic conditions requiring gastric resection remains at the center of curative outcomes, while epidemiologic changes and multimodality treatment options have evolved rapidly. Putative quality metrics for gastrectomy such as R0 rate, total lymph node (LN) count or postoperative morbidity may depend partly on changing disease and treatment patterns, and deserve evaluation under various practice conditions. Methods: Data within a U.S.-based single surgical oncologist's practice over 15 years were prospectively recorded and retrospectively analyzed for clinicopathologic factors, operative treatment aspects and outcomes. Trends and spectrum changes over three time intervals were analyzed with contingency analysis and continuous data comparative statistics. Results: Of 179 patients undergoing gastric resection, 119 were male and 60 female, with a median age of 63 years (range, 24-98 years). Resections included 56 total, 56 subtotal/distal, 30 proximal and 37 segmental gastrectomies. Diagnoses included 96 GCs, 31 gastroesophageal (GE) junction (GEJ) cancers, 21 GI stromal tumors (GISTs), and 31 other conditions. Significant trends from first towards last time interval were observed for resection type (16% to 32% proximal, 9% to 30% segmental, P=0.0003), curative intent (76% to 98%, P=0.002), diagnosis (5% to 42% GEJ cancer, P<0.0001) and preoperative therapy use (0% to 58%, P<0.0001), among others. Intraoperative aspects showed significantly reduced blood loss (median: 500 to 150 mL) and transfusion requirements (39% to 4%), and an increased use of minimally invasive techniques over time (all at P<0.001). Among patients undergoing curative intent GC resection with LN dissection, total LN counts remained steady (mean: 26), while the number of involved LNs decreased (9.0 to 3.7, P=0.0003) and the R0 resection rate increased from 74% to 85% (P=0.05). The number of specimens with >15 LNs examined increased from 69.0% to 92.5% (P=0.022). At the same time, spleen preservation rate (91% overall) and major morbidity (16%) remained unchanged throughout. Postoperative length of stay decreased from a median of 12 to 8 days (P<0.0001). Conclusions: This experience represents some variable practice patterns within a clinicopathologic spectrum of GE diseases. Postoperative or oncologic quality metrics have been sustained or did improve, which would support their utility for various practice settings; they compare favorably to other published U.S. experiences during the same time period.
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    Experience with a simplified feeding jejunostomy technique for enteral nutrition following major visceral operations
    (AME Publishing Company, 2018-07-19) Minarich, Michael J.; Schwarz, Roderich E.; Surgery, School of Medicine
    Background: Background: Perioperative nutrition support has been shown to impact on outcomes for patients with gastrointestinal cancer. Postoperative benefits of feeding tubes must be weighed against morbidity related to placement and use. A simplified jejunostomy tube technique was evaluated for outcomes. Methods: A 16-Fr rubber tube is secured at the jejunal entry site without Witzel tunnel, followed by a continuous, circumferential and alternating suture between jejunal wall and parietal peritoneum. Prospectively collected data were analyzed. Results: The technique was performed in 343 of 803 major hepatopancreatobiliary and upper gastrointestinal (GI) resections (43%). Of these patients (male =57%, median age: 65.8 years, range, 24.0-98.0 years), 89% had a cancer diagnosis. The procedures included pancreatectomy (n=189, 55%), gastrectomy (n=109, 32%), esophagectomy (n=19, 6%) and others (n=26, 7%). The operative intent was curative in 78%, palliative in 10%, or combined in 12% of patients. Postoperative morbidity rate was 40%, with 19 lethal events (5.5%), and a median length of stay of 10 days (range, 4-111 days). Tube feeds were administered in 139 patients (41%), and in 17% continued beyond discharge. Use of the feeding tube was linked to treatment interval, length of stay, major complication grade (all at P<0.0001), metastatic stage (P=0.0007) and noncurative intent (P=0.001). Tube feeds beyond discharge were associated with time interval (P<0.0001), length of stay (P=0.0006) and noncurative intent (P=0.014). Tube-specific events in 38 patients (11%) were all minor, without any intraabdominal leak, infection or obstruction. Conclusions: The technique described is safe and expedient, and the overall tube-related morbidity is low. This procedure can be recommended in cases at risk for major morbidity and nutrition support needs.
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    Fifteen-year experience with pericardiectomy at a tertiary referral center
    (BMC, 2021-06-22) Faiza, Zainab; Prakash, Anjali; Namburi, Niharika; Johnson, Bailey; Timsina, Lava; Lee, Lawrence S.; Medicine, School of Medicine
    Purpose: Pericardiectomy has traditionally carried relatively high perioperative mortality and morbidity, with few published reports of intermediate- and long- term outcomes. We investigated our 15-year experience performing pericardiectomy at our institution. Methods: Retrospective study of all patients who underwent pericardiectomy at our institution between 2005 and 2019. Baseline demographics, intraoperative details, and postoperative outcomes including long-term survival were analyzed. Results: Sixty-three patients were included in the study. 66.7% of subjects underwent isolated pericardiectomy while 33.3% underwent pericardiectomy concomitantly with another cardiac surgical procedure. The most common indications for pericardiectomy were constrictive (79.4%) and hemorrhagic (9.5%) pericarditis. Preoperatively, 76.2% of patients were New York Heart Association class II and III, while postoperatively, 71.4% were class I and II. One-, three-, five-, and ten- year overall mortality was 9.5, 14.3, 20.6, and 25.4%, respectively. Overall pericarditis recurrence rate was 4.8%. Conclusion: Pericardiectomy carries relatively high overall mortality rates, which likely reflects underlying disease etiology and comorbidities. Patients with prior cardiac intervention, history of dialysis, and immunocompromised state are associated with worse outcomes.
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    Lumbar Fusion and Decompression in American Indian, Alaskan Native, Native Hawaiian, and Pacific Islander Populations: Healthcare Disparities in Spine Surgery
    (Springer Nature, 2025-03-29) Khan, Mohammad F.; Patel, Saarang; Putzler, Dillon H.; Albert, Avi N.; Khan, Hibbah I.; Gensler, Ryan T.; Abella, Maveric; Hayashi, Jeffrey; Paulo, Frishan O.; Gendreau, Julian L.; Bow-Keola, Janette; Finlay, Andrea; Amanatullah, Derek F.; Noh, Thomas; Neurological Surgery, School of Medicine
    Introduction: Racial disparities in surgical outcomes are well documented, yet data on American Indian/Alaskan Native (AI/AN) and Native Hawaiian/Pacific Islander (NH/PI) populations remain limited. This study examines disparities in 30-day outcomes following lumbar decompression and fusion in these underrepresented groups. Materials and methods: A retrospective analysis was conducted using the American College of Surgeons National Surgical Quality Improvement Program database (2017-2020). Patients undergoing lumbar decompression and fusion were identified via current procedural terminology codes. Multivariable logistic regression models adjusted for demographic and clinical factors assessed associations between race/ethnicity and postoperative outcomes, including readmission, complications, reoperation, and non-home discharge. Adjusted odds ratios (AOR) with 95% confidence intervals (CI) were reported. Results: Among 113,340 patients, 0.38% (n=429) were AI/AN patients and 0.20% (n=229) were NH/PI patients. Compared to non-Hispanic White patients, AI/AN patients had higher odds of readmission (AOR: 1.023, 95% CI: 1.003-1.043, p=0.026) and complications (AOR: 1.030, 95% CI: 1.004-1.056, p=0.023). NH/PI patients had increased odds of readmission (AOR: 1.033, 95% CI: 1.006-1.062, p=0.018), major complications (AOR: 1.029, 95% CI: 1.007-1.051, p=0.009), and reoperation (AOR: 1.035, 95% CI: 1.014-1.057, p=0.001). Conclusions: AI/AN and NH/PI patients face higher risks of adverse postoperative outcomes following lumbar spine surgery. Targeted interventions and increased inclusion in surgical disparities research are needed to improve equity in spine care.