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Item Art Therapy in Opiate Use Disorder: Moving Toward an Integrated Treatment Framework(2021-05) Sentir, Alena; Misluk, EileenDrug addiction is a major public health concern resulting in deleterious consequences to individuals and society. Yet, addiction is a recoverable disease with the right support. Although evidence-based treatments exist for opiate use disorder, many individuals remain treatment refractory and die from overdoses. These individuals often present to treatment with dual diagnosis and polysubstance use, which are conditions that increase client complexity and barriers to recovery. An integrative systematic literature review was conducted to examine how art therapy has been used in these populations and ways that it could be incorporated into current addiction neuroscience treatment. The culmination is a six-session proposal with the goal of increasing treatment retention in refractory populations. Through the framework of the Expressive Therapies Continuum and modern addiction neuroscience treatment, the proposal is theorized to integrate limbic to cortical functioning, stimulate motivation, increase empowerment, and support clients during recovery. Though the proposal gives special consideration to those with opiate use disorder in medication-assisted treatment, it inclusive of other substance use disorders and accounts for various client complexities, as well as being easily adaptable by an art therapist to different treatment settings.Item Naloxone-associated pulmonary edema in a 3-year-old with opioid overdose(Wiley, 2022-05-23) Grout, Sarah; Dave, Madhuri; Lefort, Roxanna; Pediatrics, School of MedicineBackground: Annually, close to 5000 children under age 6 years are treated in emergency departments or admitted for care due to opioid exposures. Naloxone is effectively used to treat opioid overdose in both children and adults. Non-cardiogenic pulmonary edema is a rare but serious adverse effect of naloxone administration that has been reported in adults. Case report: We present the case of a 3-year-old male with suspected opioid overdose who developed acute hypoxia due to pulmonary edema after administration of naloxone following a likely prolonged downtime. Why should an emergency physician be aware of this?: The copious fluid in the airway made for difficult intubation at a pediatric tertiary care center. Given the incidence of opioid exposures in children, clinicians should be aware of this rare, but dangerous adverse effect of naloxone and consider airway precautions and pediatric critical care availability early in the presentation.Item The Interaction of Opiate Misuse and Marijuana Use on Behavioral Health Outcomes using the Traumatic Brain Injury Model Systems Pain Collaborative Dataset(Wolters Kluwer, 2024) Callender, Librada; Lai, Tony; Driver, Simon; Ketchum, Jessica M.; Ochoa, Christa; Corrigan, John D.; Hammond, Flora M.; Harrison-Felix, Cindy; Martin, Aaron M.; Rabinowitz, Amanda R.; Starosta, Amy J.; Dubiel, Randi; Physical Medicine and Rehabilitation, School of MedicineObjective: To determine if the interaction of opiate misuse and marijuana use frequency is associated with behavioral health outcomes. Setting: Community. Participants: Three thousand seven hundred fifty participants enrolled in the Traumatic Brain Injury Model Systems who completed the Pain Survey and had complete opioid use and marijuana use information. Design: Cross-sectional, secondary analysis from a multisite observational cohort. Main outcome measures: Clinically significant behavioral health symptoms for posttraumatic stress disorder (PTSD), depression, anxiety, and sleep quality. Results: Three thousand five hundred thirty-five (94.3%) participants did not misuse opiates, 215 (5.7%) did misuse opiates (taking more opioid pain medication than prescribed and/or using nonprescription opioid pain medication); 2683 (70.5%) participants did not use marijuana, 353 (9.3%) occasionally used marijuana (less than once a week), and 714 (18.8%) regularly used marijuana (once a week or more frequently). There was a statistically significant relationship (P < .05) between the interaction of opiate misuse and marijuana use frequency and all behavioral health outcomes and several covariates (age, sex, cause of injury, severity of injury, and pain group category). Pairwise comparisons confirm that statistically significant associations on behavioral health outcomes are driven by endorsing opiate misuse and/or regular marijuana use, but occasional marijuana use was not associated. Conclusions: Higher odds of clinically significant PTSD, depression, anxiety, and poor sleep quality are present in people with traumatic brain injury (TBI) who misuse opiates and/or who use marijuana regularly. In the absence of opiate misuse, regular marijuana use had higher odds of worse behavioral health outcomes than occasional and no use. The interaction of opiate misuse and regular marijuana use yielded the highest odds. Individuals with TBI should be informed of the relationship of substance use and behavioral health outcomes and that current chronic pain may mediate the association.