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Item Is the Diabetic Bladder a Neurogenic Bladder? Evidence from the Literature(Springer, 2014-12) Powell, C.R.; Urology, School of MedicineDiabetes can often cause LUTS. This has been called diabetic cystopathy by many authors, but no concise grouping of symptoms for this condition has been agreed upon. The etiology of diabetic cystopathy remains unknown, but evidence from the literature strongly suggests a neurologic etiology as the primary factor, with other factors such as polyuria, damage to muscle from oxidative stress, and urothelial factors possibly contributing. Once a standard definition for diabetic cystopathy can be agreed upon, prospective, longitudinal studies will play a key role in the generation of hypotheses for the causes of diabetic cystopathy. Animal models will help test these hypotheses and possibly provide strategies for prevention.Item Research Needs for Effective Transition in Lifelong Care of Congenital Genitourinary Conditions: A Workshop Sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases(Elsevier, 2017-05) Hsieh, Michael; Wood, Hadley M.; Dicianno, Brad E.; Dosa, Nienke P.; Gomez-Lobo, Veronica; Mattoo, Tej K.; Misseri, Rosalia; Norton, Jenna M.; Sawin, Kathleen J.; Scal, Peter; Wright, James E.; Star, Robert A.; Bavendam, Tamara; Urology, School of MedicineOver the last 5 decades, health-care advances have yielded quantum improvements in the life expectancy of individuals with congenital genitourinary conditions (CGCs), leading to a crisis of care. Many individuals with CGC enter adulthood unprepared to manage their condition. Pediatric CGC specialists lack training to manage adulthood-related health-care issues, whereas adult genitourinary specialists lack training within the context of CGCs. To address these challenges, the National Institutes of Diabetes and Digestive and Kidney Diseases convened individuals with CGCs and experts from a variety of fields to identify research needs to improve transitional urology care. This paper outlines identified research needs.