Browsing by Subject "Myelomagenesis"

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    The Chromosome 13 Conundrum in Multiple Myeloma
    (American Association for Cancer Research, 2020-06-22) Walker, Brian A.; Medicine, School of Medicine
    In this issue of Blood Cancer Discovery, Chesi and colleagues have performed a series of mouse experiments, combined with patient sample analysis, to delineate the role of del(13) in multiple myeloma. They identify loss of the miRNA cluster MIR15A/16-1 as critical for myelomagenesis and progression of disease.