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Item Age‐dependent white matter disruptions after military traumatic brain injury: Multivariate analysis results from ENIGMA brain injury(Wiley, 2022) Bouchard, Heather C.; Sun, Delin; Dennis, Emily L.; Newsome, Mary R.; Disner, Seth G.; Elman, Jeremy; Silva, Annelise; Velez, Carmen; Irimia, Andrei; Davenport, Nicholas D.; Sponheim, Scott R.; Franz, Carol E.; Kremen, William S.; Coleman, Michael J.; Williams, M. Wright; Geuze, Elbert; Koerte, Inga K.; Shenton, Martha E.; Adamson, Maheen M.; Coimbra, Raul; Grant, Gerald; Shutter, Lori; George, Mark S.; Zafonte, Ross D.; McAllister, Thomas W.; Stein, Murray B.; Thompson, Paul M.; Wilde, Elisabeth A.; Tate, David F.; Sotiras, Aristeidis; Morey, Rajendra A.; Psychiatry, School of MedicineMild Traumatic brain injury (mTBI) is a signature wound in military personnel, and repetitive mTBI has been linked to age‐related neurogenerative disorders that affect white matter (WM) in the brain. However, findings of injury to specific WM tracts have been variable and inconsistent. This may be due to the heterogeneity of mechanisms, etiology, and comorbid disorders related to mTBI. Non‐negative matrix factorization (NMF) is a data‐driven approach that detects covarying patterns (components) within high‐dimensional data. We applied NMF to diffusion imaging data from military Veterans with and without a self‐reported TBI history. NMF identified 12 independent components derived from fractional anisotropy (FA) in a large dataset (n = 1,475) gathered through the ENIGMA (Enhancing Neuroimaging Genetics through Meta‐Analysis) Military Brain Injury working group. Regressions were used to examine TBI‐ and mTBI‐related associations in NMF‐derived components while adjusting for age, sex, post‐traumatic stress disorder, depression, and data acquisition site/scanner. We found significantly stronger age‐dependent effects of lower FA in Veterans with TBI than Veterans without in four components (q < 0.05), which are spatially unconstrained by traditionally defined WM tracts. One component, occupying the most peripheral location, exhibited significantly stronger age‐dependent differences in Veterans with mTBI. We found NMF to be powerful and effective in detecting covarying patterns of FA associated with mTBI by applying standard parametric regression modeling. Our results highlight patterns of WM alteration that are differentially affected by TBI and mTBI in younger compared to older military Veterans.Item The impact of combat deployment experiences on intimate partner violence in the Air Force(2017-08-07) Hyer, Steven Matthew; Daley, James G.; Adamek, Margaret E.; Kondrat, David C.; Seybold, PeterIntimate partner violence is a problem in the United States (U.S.) military. Previous research has identified factors that increase a couple’s risk for engaging in violence. Most of these factors, such as age, alcohol, and relationship satisfaction are consistent across civilian and military samples. One factor that is unique to military samples is deployment; service members can be exposed to unique traumatic incidents while deployed which are generally unknown to most civilians. Deployments can also increase a service member’s risk for developing Post Traumatic Stress Disorder (PTSD), which can increase their risk for intimate partner violence. Previous research on the effect of deployments on intimate partner violence has produced mixed results. The purpose of this study was to analyze if deployment, total length of deployment, combat experiences from deployment, and PTSD symptoms increased risk for Air Force airmen to perpetrate intimate partner violence at a moderate or severe level of violence. Survey data from a representative sample of active duty Air Force airmen (N = 1,501) was used to conduct Chi-Square analyses and multinomial logistic regression models for perpetrated violence. Results of the study showed that deployment and combat experiences were not significant predictors of perpetrated violence. PTSD symptoms, in addition to alcohol misuse and relationship satisfaction, were significant predictors of moderate and severe perpetrated violence. In terms of practice and policy implications, the study results underscore the importance of widespread screening for these risk factors as well as the availability of interventions focused on alcohol use and relationship issues among service members. Future research could determine if PTSD symptoms moderate the relationship between combat experiences and intimate partner violence.Item Instruction - Subject: Conscientious objectors(2007-05-31) Department of Defense, U.S.Item The Military Selective Service Act, 50 U.S.C. App. 451 et seq.(http://www.sss.gov/pdfs/mssa-2003.pdf, 2003-07-09)Item Reducing veterans’ risk for suicidal behaviors: a qualitative study to inform development of the RECLAIM health promotion program(BMC, 2020-08-01) Shue, Sarah; Brosmer, Jayme; Matthias, Marianne S.; Psychology, School of ScienceBackground In an effort to reduce the high rate of suicide among post-9/11 veterans, a collaborative team within the Department of Veterans Affairs (VA) has developed a holistic community-based health promotion program designed to facilitate social and self-connectedness. The purpose of this study was to elicit veteran and stakeholder feedback to prepare the program for piloting and implementation. Methods Focus groups and interviews were conducted with post-9/11 veterans and veteran stakeholders (e.g., VA clinicians) to elicit feedback regarding the health promotion program. Focus groups and interviews were audio-recorded and transcribed. Qualitative thematic analysis identified key themes emerging from the focus groups and interviews. Results Seven focus groups (3 Veteran groups, 4 stakeholder groups) and 3 interviews (2 Veterans, 1 stakeholder) were conducted with 41 participants (14 veterans, 27 stakeholders). Overall, participants had a positive perception of the program. Thematic analysis revealed shared perspectives that provided insight into 1) enhancing program recruitment and retention, 2) the perceived ability of a health promotion program to provide more holistic, veteran-centered care, and 3) using health promotion programs to help veterans establish structure in their daily lives. Conclusions Findings indicated an overall acceptance of the program, and participants’ perspectives on how to reduce barriers and enhance facilitators can inform the development of a larger-scale health promotion program that can be tested through future research. While discussion questions were specifically focused on the program in this study, findings can be considered more broadly for the design and implementation of related programs to effectively improve the health and wellness of post-9/11 veterans.