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Item Associations between Benign Cutaneous Nevi and Risk of Type 2 Diabetes Mellitus in Men and Women: Results from Two Prospective Cohort Studies(Office of the Vice Chancellor for Research, 2015-04-17) Dai, Hongji; Sun, Qi; Zhang, Xi; Manson, JoAnn E.; Hu, Frank B.; Song, YiqingABSTRACT Objective: Previous studies suggest that the number of cutaneous nevi and type 2 diabetes mellitus (T2DM) are both associated with endogenous sex hormone levels. However, no prospective studies have specifically examined the relationship between the number of benign cutaneous nevi and T2DM. Research Design and Methods: We prospectively examined the associations between the number of nevi and risk of T2DM among 23,748 men (1986-2010) from the Health Professionals Follow-up Study (HPFS) and 67,050 women (1989-2010) from the Nurses' Health Study (NHS). Information on the numbers of melanocytic nevi on arms and the incidence of T2DM was collected by validated questionnaires. Results: During 1,831,118 person-years of follow-up, we documented 8748 incident cases of T2DM. After adjustment for age, BMI, and other diabetes risk factors, the number of nevi was significantly associated with increased risk of T2DM. Multivariable-adjusted HRs (95% CIs) for <1, 1-5, 6-14, and ≥15 nevi were 1.00 (reference), 1.02 (0.92, 1.14), 1.10 (0.87, 1.38), and 1.70 (1.22, 2.36), respectively, for men (P trend = 0.03) and 1.00 (reference), 1.15 (1.09, 1.21), 1.25 (1.11, 1.40), and 1.70 (1.38, 2.09), respectively, for women (P trend = 0.019). This positive association remained consistent across subgroups of participants. Conclusions: Mole count may represent a novel marker for development of T2DM in men and women, indicating a unique nevus development-related mechanism, possibly due to altered levels or functions of endogenous steroid sex hormones, in the pathogenesis of T2DM. Further studies are warranted to clarify the relationship of nevogenesis and T2DM and underlying mechanisms.Item Delay in Seeking Healthcare Services Following Onset of Urethritis Symptoms in Men(Wolters Kluwer, 2019-05) Aaron, Kristal J.; Van Der Pol, Barbara; Jordan, Stephen J.; Schwebke, Jane R.; Hook, Edward W., III; Medicine, School of MedicineBackground: Symptom awareness, behavioral factors, and other barriers associated with timely sexually transmitted infection (STI) health care provision in men is not well studied. Methods: Men attending an STI clinic answered a questionnaire regarding their symptoms, sexual behavior, and sociodemographic and behavioral characteristics. Characteristics of symptomatic men were compared between those who did and did not delay seeking health care services. Delayed care seeking was defined as clinic attendance longer than 7 days after symptoms, whereas early care seeking was defined as clinic attendance of 7 days or less. Results: Over a quarter (n = 43 [27.7%]) of men with urethritis symptoms (urethral discharge or dysuria) delayed seeking care for more than 7 days. Compared with men who sought treatment within 7 days, those that delayed care worried for longer periods that their symptoms were STI-related, were more likely to attempt self-treatment of STI symptoms, were more likely to continue engaging in sexual activity, and were less likely to use a condom during their last sexual encounter. Conversely, men that delayed care seeking were less likely to have urethral discharge on physical examination, to have 5 or more polymorphonuclear leukocytes, and to test positive for Neisseria gonorrhoeae. When compared with men that sought care earlier, men that delayed care seeking had fewer overall and new partners in the past 30 days. Conclusions: Our data suggest that over a quarter of men aware of STI symptoms delay seeking health services. Interventions that promote better patient understanding of the importance of symptom recognition and that facilitate timely access to care may provide new opportunities to reduce STI transmission.Item Man suffering from discrete smallpox.(Indiana State Board of Health, 1903-07)A severe case of discrete smallpox. Never vaccinated.Item Man suffering from smallpox(Indiana State Board of Health, 1904-09)Frank Luther, unvaccinated, in height of smallpox.Item Photograph of four men suffering from smallpox.(Indiana State Board of Health, 1899-11)These colored men were never vaccinated. If they had been they almost certainly would have excaped the loathsome smallpox. The expense to the public of quarantine and care, the hindrance to business and the alarm caused by smallpox may all be avoided by vaccination. Practical people will apply to everyday life the discoveries of science.Item Severe case of confluent smallpox.(Indiana State Board of Health, 1903-07)Very severe confluent smallpox. Never vaccinated. Recovered.Item Warren Beatty and the Elusive Male Body in Hollywood Cinema(© 1994 Dennis Bingham. [BREAK]The definitive version of the article is available at: [LINK]http://hdl.handle.net/2027/spo.act2080.0033.001:29[/LINK].[BREAK] Access to the original article may require subscription and authorized logon ID/password. IUPUI faculty/staff/students please check University Library resources before purchasing an article. Questions on finding the original article via our databases? Ask a librarian: [LINK] http://www.ulib.iupui.edu/research/askalibrarian[/LINK]., 1994) Bingham, Dennis, 1954-It is said that the movies, and more recently TV, are a school in which males learn the strategies and discourse of sexual engagement. How much more complex the situation has become in the last few decades is discussed.Item Where Do Men and Women Give? Gender Differences in the Motivations and Purposes for Charitable Giving(2015-09) Mesch, Debra; Osili, Una; Ackerman, Jacqueline; Dale, ElizabethThis study seeks to explore gender differences in the purpose and motivations for charitable giving. We analyze new waves of data from the Philanthropy Panel Study, the Bank of America/U.S. Trust Studies of High Net Worth Philanthropy, and the Million Dollar List to investigate where men and women direct their charitable gifts, the influence of charitable decision making on giving, and why men’s and women’s priorities may differ. We find that generally, women are more likely than men to give to every charitable subsector except neighborhoods and communities and tend to spread their giving out. However, high net worth women exhibit fewer differences in their giving as compared to high net worth men. Women prioritize issues and areas such as women’s rights, human rights, and the environment, while men favor the economy and national security. Finally, we find that women are generally motivated to give by their political or philosophical beliefs or their involvement in an organization.