Browsing by Subject "Mediastinal tumors"

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    Mediastinal Germ Cell Tumors: Updates in Diagnosis and Management
    (Elsevier, 2020-10) Stram, Amanda R.; Kesler, Kenneth A.; Surgery, School of Medicine
    Primary mediastinal nonseminomatous germ cell tumors represent a rare but important malignancy that occurs in otherwise young and healthy patients. Treatment is challenging and involves cisplatin-based chemotherapy followed by surgery to remove residual disease. Avoiding bleomycin-containing chemotherapy in the treatment of primary mediastinal nonseminomatous germ cell tumors is important. Prechemotherapy and postchemotherapy pathology as well as postoperative serum tumor markers are independent predictors of long-term survival.