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Item An Investigation of Intermaxillary Tooth Mass Discrepancy: A New Approach(1974) Williams, James E.; Garner; Tomich; Potter; Dirlam; ShanksThis study investigated the incidence, amount, and location of intermaxillary tooth mass discrepancy in a sample of malocclusion cases. Obtaining accurate tooth measurements was a primary concern of the investigation. Interproximal separation was achieved in each case prior to the taking of a silicone rubber impression. Individual tooth dies were then produced from the impression and measured with direct reading instruments. A model of occlusion was adopted as a reference for evaluating tooth mass problems. Each case demonstrated some tooth mass discrepancy. The discrepancies in the posterior segments were generally very minor and of limited clinical significance. Larger discrepancies were found in the anterior segments. Most of these were small enough to be managed by clinical manipulation of tooth position, but approximately one-fifth were large enough to have significant effects on occlusion. The labia-lingual thickness of incisors was found to have considerable potential in affecting the anterior occlusion. Statistical analysis revealed no difference in the amount of tooth mass discrepancy between males and females. Likewise, there was no difference between Class I and Class II malocclusion groups. An anterior ratio and ''Anterior Percentage Relation" were calculated and they compared favorably with the results of the original investigators. The malocclusion cases had a wider range of values than those cases of excellent occlusion. Right-left tooth size asymmetry was investigated. The results indicated that the problem is not nearly as great as previously reported.Item Antero-Posterior Movement of the Maxillae with a Modified Sutural Expansion Device(1967) Gersh, Gary PaulIt was the purpose of this study to discover if anteroposterior movement of the maxillary bones was possible. Seven cats were used as the experimental animals. An expansion device which produced a diagonal force from one maxillary cuspid to the opposite molar was inserted in five of the animals. Two animals were used as controls. The effects of the lateral and antero-posterior components of the force were studied by means of before and after models, oriented occlusal radiographs, and histologic sections. Antero-posterior movement did occur. The anterior movement was more evident than the posterior movement due to the response evoked in the premaxillary-maxillary and the maxillary-palatine sutures. The sutures which were compressed showed very little response when viewed in horizontal histologic sections as compared to the sutures which were under tension. The sutures under tension showed marked osteophytic production which generally grew parallel to the line of force application. This difference in response allowed one side to remain as an anchorage unit while the opposite side moved anteriorly. The lateral increase in width appeared to be stable. In one animal the force was removed for thirty six days prior to sacrifice. In this animal the stability of the antero-posterior movement was questionable.Item Comparison of movement rate with different initial moment-to-force ratios(Elsevier, 2019-08-01) Li, Shuning; Chen, Jie; Kula, Katherine S.; Mechanical Engineering and Energy, School of Engineering and TechnologyIntroduction: The objective of this clinical prospective study was to evaluate the effect of the two treatment strategies, translation or controlled tipping followed by root correction, on canine retraction efficiency, specifically canine movement rate. Methods: Twenty-one patients who needed bilateral maxillary canine retraction to close extraction space as part of their treatment plan were selected for this study. Segmental T-loops designed for controlled tipping or for translation were applied randomly to each side. Two digital maxillary dental casts (taken pre- and post-treatment) were used to measure the tooth displacements of each patient. The coordinate system located at the center of canine crown on the pre-treatment model with the three axes defined in the mesial-distal (M-D), buccal-lingual (B-L), and occlusal-gingival (O-G) directions was used to express the six tooth displacement components. The movement rates on the occlusal plane and in the M-D direction were computed. Movement rates were calculated by dividing the M-D displacements or the resultant displacement on the occlusal plane with the corresponding treatment time. Results: T-loops for controlled tipping moved canines faster (33.3% on occlusal plane and 38.5% in the M-D direction) than T-loops for translation. The differences are statistically significant (p = 0.041 on the occlusal plane and 0.020 in the M-D direction). Conclusion: 1. Moment-to-force ratio (M/F) impacts on the canine movement rate in a maxillary canine retraction treatment with segmented T-loop mechanism. 2. Within the neighborhood of the ratio for translation, lower M/F moves canine faster than higher M/F both on occlusal plane and in the M-D direction.Item Diagnostic efficacy of novel cephalometric parameters for the assessment of vertical skeletal dysplasia(Tabriz University of Medical Sciences, 2022) Gandhi, Kaveri Kranti; Rai, Anshu; Periodontology, School of DentistryBackground. An accurate diagnosis of vertical skeletal abnormalities presents several challenges. Specific cephalometric parameters can be effectively used for this purpose; however, the diagnostic accuracy of these parameters has not been entirely ascertained. This study examines the effectiveness of two novel cephalometric parameters for diagnosing vertical dysplasia. Methods. In this retrospective study, orthodontic patients were distributed into three study groups: average growth (AGG), horizontal growth (HGG), and vertical growth (VGG). The efficacies of the sum of angles (maxillary, mandibular, and ramal) and the height ratio (lower anterior facial height [LAFH]/upper anterior facial height [UAFH]) in identifying different growth patterns were examined. Receiver operating characteristic (ROC) curves were employed to assess the diagnostic precision quantitatively. Results. A total of 150 patients were included and divided equally among the three study groups. The ramal and mandibular angles varied across AGG, HGG, and VGG; however, the maxillary angle and the sum of these three angles did not vary significantly. There was a substantial variance in LAHF, UAHF, and their ratio in the three groups. The height ratio had 88% and 92% sensitivity to diagnose VGG and HGG, with cut-off values of 46 and 34, respectively (P<0.001). Conclusion. Height ratio values varied considerably depending on the facial growth patterns, suggesting its efficacy as a diagnostic tool for skeletal dysplasia, with greater reliability for positive treatment outcomes.Item DNA ploidy analysis of primary lymphoma of bone from mandible and maxilla(1993) Hughes, RoseannItem Effects of rapid maxillary expansion on the cranial and circummaxillary sutures(Elsevier, 2011-10) Ghoneima, Ahmed; Abdel-Fattah, Ezzat; Hartsfield, James; El-Bedwehi, Ashraf; Kamel, Ayman; Kula, Katherine; Department of Orthodontics and Oral Facial Genetics, IU School of DentistryINTRODUCTION: The aim of this study was to determine whether the orthopedic forces of rapid maxillary expansion cause significant quantitative changes in the cranial and the circummaxillary sutures. METHODS: Twenty patients (mean age, 12.3 ± 1.9 years) who required rapid maxillary expansion as a part of their comprehensive orthodontic treatment had preexpansion and postexpansion computed tomography scans. Ten cranial and circummaxillary sutures were located and measured on one of the axial, coronal, or sagittal sections of each patient's preexpansion and postexpansion computed tomography scans. Quantitative variables between the 2 measurements were compared by using the Wilcoxon signed rank test. A P value less than 0.05 was considered statistically significant. RESULTS: Rapid maxillary expansion produced significant width increases in the intermaxillary, internasal, maxillonasal, frontomaxillary, and frontonasal sutures, whereas the frontozygomatic, zygomaticomaxillary, zygomaticotemporal, and pterygomaxillary sutures showed nonsignificant changes. The greatest increase in width was recorded for the intermaxillary suture (1.7 ± 0.9 mm), followed by the internasal suture (0.6 ± 0.3 mm), and the maxillonasal suture (0.4 ± 0.2 mm). The midpalatal suture showed the greatest increase in width at the central incisor level (1.6 ± 0.8 mm) followed by the increases in width at the canine level (1.5 ± 0.8 mm) and the first molar level (1.2 ± 0.6 mm). CONCLUSIONS: Forces elicited by rapid maxillary expansion affect primarily the anterior sutures (intermaxillary and maxillary frontal nasal interfaces) compared with the posterior (zygomatic interface) craniofacial structures.Item A Histologic and Cephalometric Investigation of Premolar Intrusion in the Macaque Speciosa Monkey(1965) Dellinger, Eugene L.It has been debated as to whether teeth may actually be intruded in their alveoli. This study was designed to measure the intrusive movement and histologic response of specific teeth to a known intrusive force. Four Macaque speciosa monkeys were used. The animals corresponded in age to a 12-14 year old human being. Intrusive forces of either 10, 50, 100, or 300 grams were placed on the maxillary first premolars; each force value was held constant during the duration of the experiment, which was 60 days. Maxillary first molars were used as anchorage. Cephalometric headplates proved that all force values were capable of giving intrusion. The 50 gram forces, however, gave the most efficient intrusion. Histologic sections were made on all experimental teeth. 300 and 100 gram forces gave excessive root resorption but the 50 and 10 gram force values elicited only slight root resorption. Root resorption seemed to be directly related to excessive force. The amount of intrusion was not related to a loss of root structure. Bone resorption appeared to allow the intrusion of teeth with minimal tissue damage if proper force values were used.Item Orthopedic Protraction of the Maxilla in Macaca Speciosa(1972) Hamilton, John G.The intent of this study was to use orthopedic forces to move the maxilla forward in Macaca speciosa (stump tailed monkeys). Three animals were fitted with helmets and facebows to serve as extraoral anchorage. Acrylic labial-lingual splints were ligated with wire around the maxillary teeth. Calibrated coil springs were placed between the splints and facebows and activated to produce forces of two, three, and four kilograms. Paired stainless steel implants had been placed to facilitate cephalometric analysis of the position of the maxilla. The period of activation was to have been thirty days. One animal escaped from the appliance within twelve hours. The other two were taken off the appliance within forty-eight hours because pressure necrosis had developed under the helmet. No data were collected. The uninjured animal was fitted with a different design of helmet and the spring was activated to produce one kilogram. After four days the animal had developed ulcers under the helmet and the experiment was terminated. Lateral headplates were taken before and after the experimental period. Cephalometric analysis and superpositioning showed no change in the position of the maxilla. It was concluded that after four days of one kilogram anterior pull the maxilla did not move. The difficulties encountered in the study defined the problem as being the attainment of suitable anchorage from which to apply the anterior orthopedic force to the maxilla. Several areas of additional research were discussed relative to achieving protraction of the maxilla.Item Relationship of Wound Healing and Angiogenesis to the Cell Kinetics of the Initial Osteogenic Response in Orthopedically Expanded Anterior Maxillary Suture in the Rat(1994-07) Chang, Hwai-nan; Roberts, W. Eugene; Chen, Jie; Christen, Arden G.; Garetto, Lawrence P.; Katona, Thomas R.; Lee, Chao-Hung; McDonald, JamesFollowing sutural expansion, wound healing and angiogenesis precede bone formation. The purpose of this study was to examine angiogenic and subsequent osteogenic responses during a 96 hour time-course following sutural expansion. Fifty rats were divided into: (1) control group that received only angiogenic induction via injection of 5 ng/gm recombinant human endothelial cell growth factor (rhECGF); (2) experimental group that received orthopedic expansion and rhECGF; (3) sham group that received expansion and NaCl injection; and (4) baseline group that received no expansion or injection. Both experimental and sham groups were subdivided further to conduct experiments of 1, 2, 3, and 4 days. All rats were injected with 3H-thymidine (1.0 μCi/gm) 1 hour before euthanasia to label DNA of S-phase cells. The premaxilla was dissected free and demineralized. Sections (4 μm thick) were stained with hematoxylin and eosin. Angiogenesis and cell migration were analyzed using a previously established cell kinetics model. The cells were divided into four categories according to nuclear volume: A cells (40-79 μm3), B cells (80-119 μm3), C cells (120-169 μm 3), and D cells (~169 μm3). ANOVA was used to test the hypothesis that enhancement of angiogenesis stimulates reestablishment of osteogenic capability. Blood vessel number, area and endothelial cell labeled index significantly increased in experimental groups, but no difference was found between control and baseline groups (i.e., rhECGF treatment alone). Labeled-pericyte index and activated pericyte's numbers in the experimental group were also higher than in the sham groups. Compared to sham groups, A+A' cell numbers were significantly higher during the first two days in the experimental groups, followed by a rapid decrease at days three and four; C+D cell number peaked at day three. These results demonstrate that supplemental rhECGF enhances angiogenesis in expanded suture but not in nonexpanded suture. Data also suggest that pericytes may serve as a bridge between angiogenesis and osteogenesis.Item A Serial Cephalometric Study of Human Maxillary Growth(1960-06-01) Callis, RobertCephalometric radiographs were obtained on 18 subjects possessing normal deciduous dentitions at a mean age of five years, three months, and again at mean ages eight years, eight months, and nine years, seven months. Nine of these were again studied at a mean age of 11 years, ten months. The discussion of growth was primarily described from a mean age of five years, three months, representing deciduous dentitions to age eight years, eight months, representing early mixed dentition, and then to age 11 years, ten months, representing early permanent dentitions. Growth increments were studied through the use of direct measurements, linear and angular, from acetate tracings. In addition, a method of superposing serial records has been presented. The method involves the use of minimally growing areas in the body of the maxilla. Nasal floor was the plane of reference, and the mean image of key ridge was used as a registration point. By utilizing this method of orientation, the effects of growth of distal structures is eliminated, and growth of the maxilla itself is more apparent. The data were subjected to statistical analysis to describe total sample measurements and increments of growth. The data were also examined to determine if any correlation exists between skeletal relationships and growth increments. In addition, individual sample variation was discussed and composite tracings of three subjects were used to describe some individual growth changes. A check on the accuracy of the measurements due to interpretation of landmarks and mechanical errors was described.