Browsing by Subject "Knox test"

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    A modified two-process Knox test for investigating the relationship between law enforcement opioid seizures and overdoses
    (The Royal Society, 2021-06) Mohler, G.; Mishra, S.; Ray, B.; Magee, L.; Huynh, P.; Canada, M.; O’Donnell, D.; Flaxman, S.; Computer and Information Science, School of Science
    Recent research has shown an association between monthly law enforcement drug seizure events and accidental drug overdose deaths using cross-sectional data in a single state, whereby increased seizures correlated with more deaths. In this study, we conduct statistical analysis of street-level data on law enforcement drug seizures, along with street-level data on fatal and non-fatal overdose events, to determine possible micro-level causal associations between opioid-related drug seizures and overdoses. For this purpose, we introduce a novel, modified two-process Knox test that controls for self-excitation to measure clustering of overdoses nearby in space and time following law enforcement seizures. We observe a small, but statistically significant (p < 0.001), effect of 17.7 excess non-fatal overdoses per 1000 law enforcement seizures within three weeks and 250 m of a seizure. We discuss the potential causal mechanism for this association along with policy implications.