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Item Behind the scenes of Indiana, which recorded the number one investment from Japan in the United States 3 Purdue University edition(JST, 2021) Kono, Tatsuyoshi; Medicine, School of MedicineItem Country Report 2018: Japan(2018) Yoshioka, Takayuki; Onishi, TamakiIn Japan, freedom of assembly, association, and expression are guaranteed under the Constitution, and there are many laws under which individuals can incorporate nonprofit organizations. The primary law for private foundations and associations is the 2008 Act on General Nonprofit Incorporated Associations and General Incorporated Foundations (⼀般社団法⼈及び⼀般財団法⼈ に関する法律). As guaranteed by this law, General Nonprofit Corporations (GNCs), which consist of General Nonprofit Incorporated Associations and Foundations, can be easily established without approval from the government and registered with a registry office. The cost is roughly 120,000 JPY (about US $1,050). As of November 2017, there are approximately 47,000 GNC Associations and 7,000 GNC Foundations (National Tax Agency figures).Item Early SNS-based monitoring system for the COVID-19 outbreak in Japan: a population-level observational study(Japan Epidemiological Association, 2020-05-30) Yoneoka, Daisuke; Kawashima, Takayuki; Tanoue, Yuta; Nomura, Shuhei; Ejima, Keisuke; Shi, Shoi; Eguchi, Akifumi; Taniguchi, Toshibumi; Sakamoto, Haruka; Kunishima, Hiroyuki; Gilmour, Stuart; Nishiura, Hiroshi; Miyata, Hiroaki; Epidemiology, School of Public HealthBackground: The World Health Organization declared the novel coronavirus outbreak (COVID-19) to be a pandemic on March 11, 2020. Large-scale monitoring for capturing the current epidemiological situation of COVID-19 in Japan would improve preparation for and prevention of a massive outbreak. Methods: A chatbot-based healthcare system named COOPERA (COvid-19: Operation for Personalized Empowerment to Render smart prevention And care seeking) was developed using the LINE app to evaluate the current Japanese epidemiological situation. LINE users could participate in the system either though a QR code page in the prefecture’s website, or a banner at the top of the LINE app screen. COOPERA asked participants questions regarding personal information, preventive actions, and non-specific symptoms related to COVID-19 and their duration. We calculated daily cross correlation functions between the reported number of infected cases confirmed by PCR and the symptom-positive group captured by COOPERA. Results: We analyzed 206,218 participants from three prefectures reported between March 5 and 30, 2020. The mean (standard deviation) age of participants was 44.2 (13.2). No symptoms were reported by 96.93% of participants, but there was a significantly positive correlation between the reported number of COVID-19 cases and self-reported fevers, suggesting that massive monitoring of fever might help to estimate the scale of the COVID-19 epidemic in real time. Conclusions: COOPERA is the first real-time system being used to monitor trends in COVID-19 in Japan, and provides useful insights to assist political decisions to tackle the epidemic.Item Evaluation of Abicipar Pegol (an Anti-VEGF DARPin Therapeutic) in Patients With Neovascular Age-Related Macular Degeneration: Studies in Japan and the United States(Slack, 2019-02) Kunimoto, Derek; Ohji, Masahito; Maturi, Raj K.; Sekiryu, Tetsuju; Wang, Ying; Pan, Grace; Li, Xiao-Yan; Schneider, Susan; Ophthalmology, School of MedicineBACKGROUND AND OBJECTIVE: To evaluate comparability of abicipar pegol (abicipar) effects in patients with treatment-naïve neovascular age-related macular degeneration (nAMD) in Japan and the United States. PATIENTS AND METHODS: Phase 2, multicenter, randomized, double-masked, 20-week studies (BAMBOO, Japan; CYPRESS, United States). Patients (n = 25 each study) received three monthly intravitreal injections of abicipar 1 mg or 2 mg or five monthly intravitreal injections of ranibizumab 0.5 mg. RESULTS: Mean best-corrected visual acuity change from baseline at week 16 (primary endpoint) for abicipar 1 mg, abicipar 2 mg, and ranibizumab was +7.8 letters, +8.9 letters, and +17.4 letters (BAMBOO); +4.4 letters, +10.1 letters, and +15.2 letters (CYPRESS). Mean central retinal thickness change from baseline was −187.3 μm, −196.5 μm, and −230.4 μm (BAMBOO); −106.5 μm, −112.8 μm, and −124.4 μm (CYPRESS). Uveitis or vitritis was reported in three abicipar-treated patients. CONCLUSION: Abicipar demonstrated extended duration of effect and safety that were comparable between Japanese and non-Japanese patients with nAMD. Abicipar effectively treated Japanese patients with polypoidal choroidal vasculopathy.Item Exploring Cultural Differences in Children’s Artistic Development: Comparing the United States and Japan(2024) Barannikova, Larisa; Misluk, Eileen; Anderson, MyrdeneThis research investigates the impact of culture on artistic development in elementary school children in the United States and Japan. A quantitative study collected drawings from six children in each of the elementary school grades of one, three, and five from both countries and rated each drawing on four developmental measures. The analysis found that children’s drawings in both cultures showed similar developmental levels according to Lowenfeld’s Stages of Artistic Development. It also found that children’s drawings in Japan in all grades had higher levels of detail and manga influence in their figure drawings compared to children in the United States. Finally, the drawings of children in Japan showed forms of spatial representation that were distinct from those of children in the United States and were not accounted for by Lowenfeld’s framework. Due to the small sample size of this study, further research is needed to assess the generalizability of these findings.Item Small and Tall: Sumi-e on Fans and Screens(The Sumi-e Society of America, Inc., 2023) Hook , Sara AnneThis article provides an overview of the tradition of sumi-e painting on fans and screens.