Browsing by Subject "Intravenous fluids"

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    New Trends in the Utilization of Intravenous Fluids
    (Cureus, 2021-04-21) Tinawi, Mohammad; Medicine, School of Medicine
    Intravenous fluids (IVFs) are the most commonly used drugs in hospitalized patients. Knowledge of the indications and pharmacokinetics of IVFs is critical for all medical disciplines. Isotonic saline (normal saline, 0.9% NS) is the most utilized intravenous solution. Isotonic saline effectively expands the intravascular compartment, as one-quarter of the infusate goes intravascularly, while the remaining three-quarters go into the interstitial space. The proper use of IVFs in different clinical scenarios is paramount. IVFs differ with regard to their half-life, intravascular volume expansion, preparation, and cost. Crystalloids are more commonly utilized due to their relatively low cost and availability. Colloids are very advantageous in cases of shock or hemorrhage, as they remain in the intravascular space, thus facilitating an increase in blood pressure (BP) prior to blood administration. Colloids are also advantageous in cases of burns and severe hypoglobulinemia. Human albumin (5%, 20%, and 25%) is the most used colloid solution. It remains intravascularly provided and there is no capillary leak as in systematic inflammation. The goal in hospitalized patients is timely and adequate intravenous fluid resuscitation. Utilization of a large volume of isotonic saline may lead to hypervolemia, hypernatremia, hyperchloremia, metabolic acidosis, and hypokalemia. The use of balanced intravenous solutions has been advocated to avoid these complications.
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    Severe Rhabdomyolysis Due to Strenuous Exercise With a Potential Role of a High-Caffeine Energy Drink
    (Cureus, 2022-01-01) Tinawi, Mohammad; Medicine, School of Medicine
    Caffeine is the core ingredient in energy drinks. These drinks are commonly consumed by athletes around the time of their workout to boost energy levels. The patient in the case presented is a 40-year-old-man who developed severe rhabdomyolysis after consuming an energy drink with high content of caffeine prior to a strenuous workout. He was successfully treated with isotonic intravenous solutions. Clinicians should be aware of the potential adverse reactions associated with the use of energy drinks.