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Item Prostate Cancer: Effects of tertiary Gleason pattern 5 on oncological outcome(Nature, 2015-04) Williamson, Sean R.; Cheng, Liang; Department of Pathology and Laboratory Medicine, IU School of MedicineThe prognostic implications of a tertiary component of Gleason pattern 5 cancer at radical prostatectomy remain incompletely understood. A newly published study highlights the relationship between tertiary pattern 5 cancer, other risk factors and clinical outcomes. Authors propose a prognostic model to identify patients with the greatest need for adjuvant therapy.