Browsing by Subject "Excel"

Now showing 1 - 2 of 2
  • Thumbnail Image
    Item
    An improved method for murine laser-induced choroidal neovascularization lesion quantification from optical coherence tomography images
    (Elsevier, 2022-08-02) Jensen, Nathan R.; Lambert-Cheatham, Nathan; Hartman, Gabriella D.; Muniyandi, Anbukkarasi; Park, Bomina; Sishtla, Kamakshi; Corson, Timothy W.; Ophthalmology, School of Medicine
    Laser-induced choroidal neovascularization (L-CNV) in murine models is a standard method for assessing therapies, genetics, and mechanisms relevant to the blinding eye disease neovascular or "wet" age-related macular degeneration. The ex vivo evaluation of these lesions involves confocal microscopy analysis. In vivo evaluation via optical coherence tomography (OCT) has previously been established and allows longitudinal assessment of lesion development. However, to produce robust data, evaluation of many lesions may be required, which can be a slow, arduous process. A prior, manual method for quantifying these lesions as ellipsoids from orthogonal OCT images was effective but time consuming. We therefore developed an OCT lesion quantification that is simplified, streamlined, and less time-consuming.
  • Thumbnail Image
    Item
    Wet Reagent Profile Sensor Visualization Tool
    (2020-04-30) Darrough, Kacie; Jackson, Caleb; Cooney, Elaine; Freije, Elizabeth
    The Wet Reagent Profile Sensor is a system that Roche Diabetes Care Indy uses in its diabetes test strip manufacturing process. The current system they are using involves a laser sensor that projects onto a wet reagent material after it is coated onto a substrate. The machine that applies the reagent uses averages of 800 measurement points taken by the laser sensor to determine whether or not the reagent is within acceptable limits. If the reagent applied to a given section of the material is not within acceptable limits, then that section is marked for rejection and later taken out of the roll. The current system does not store the data that is collected, display it in an easily accessible manner, nor provide direct access to the 800-point profiles. No variable option currently exists for the data collection rate and the sponsor would prefer a variable option, if possible. The objective of this project is to store and display all 800 points of data in a profile, change the frequency at which data is collected, and display a 3-D visual of the profiles. These changes and additions should be accomplished while avoiding interference with the normal production process. During the first phase of this project, the student engineers have begun analyzing the system, making design decisions and choosing between different components, planning hardware and software connections, and designing an interface for the system. In the second phase of this process, students began working with Excel, which is the software that was chosen at the end of the first phase, as well as working with the controller in order to communicate serially to a computer. Due to the change of circumstances that occurred in the middle of the second phase, students could no longer test communication options with the controller. The testing and verifying stages of the project were concluded at this point and students were asked to focus on documentation. Students created a new document that discussed all of the decisions that were made throughout the project, if the decision was used, and why or why not. Test plans were revised and updated as well.