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Item Effects of estrogen depletion and drug treatment on collagen microstructure: implications(SpringerNature, 2015-05-27) Wallace, Joseph M.; Bone, Henry G.; Department of Biomedical Engineering, School of Engineering and TechnologyCommentary on: Cauble MA, Rothman E, Welch K, Fang M, Duong LT, Pennypacker BL, Orr BG, Holl MMB. Alteration of Type I collagen microstructure induced by estrogen depletion can be prevented with drug treatment. BoneKEy 2015; 4: 697. doi:10.1038/ bonekey.2015.66.