Browsing by Subject "Drug"

Now showing 1 - 4 of 4
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    Polypharmacy Among Prescription Drug Users
    (The Center for Health Policy, 2017-08-01) Omenka, Issac; Greene, Marion S.
    Polypharmacy, i.e., the misuse of multiple prescription drugs or prescription medication with other substances, is highly problematic. Whether unintentional or deliberate, misuse of multiple drugs can lead to adverse effects including addiction; drug-drug interactions; and overdose, potentially resulting in death. Polypharmacy is not uncommon; almost 84 percent of prescription drug misusers receiving substance abuse treatment in Indiana reported using at least one additional substance, most commonly alcohol or marijuana.
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    Substance Abuse in Indiana: An Urban-Rural Perspective
    (The Center for Health Policy, 2017-06-01) Kooreman, Harold E.; Greene, Marion S.
    The use of alcohol and drugs is a significant public health problem in the United States. Indiana, like many other states in the nation, is lacking in substance abuse treatment services and rural areas are particularly underserved. Rural residents may encounter additional barriers to receiving substance abuse treatment, including stigma, fear that they may know their treatment providers, a lack of access to specialized services, inferior quality of care, and having to pay more for treatment.
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    Substance Abuse Trends in Indiana: A 10-Year Perspective
    (The Center for Health Policy, 2017-04-01) Balio, Casey; Greene, Marion S.
    Substance use is a significant public health problem in the United States. Excessive use of alcohol and drugs has been linked to increased morbidity and mortality from cardiovascular conditions; injuries and motor vehicle crashes; sexually transmitted and blood-borne illnesses, including HIV/AIDS and hepatitis B and C, resulting from risky sexual behaviors and/or injection drug use; pregnancy complications and neonatal abstinence syndrome (NAS); and drug overdoses [5, 6].
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    The collaborative study on the genetics of alcoholism: Sample and clinical data
    (Wiley, 2023) Dick, Danielle M.; Balcke, Emily; McCutcheon, Vivia; Francis, Meredith; Kuo, Sally; Salvatore, Jessica; Meyers, Jacquelyn; Bierut, Laura J.; Schuckit, Marc; Hesselbrock, Victor; Edenberg, Howard J.; Porjesz, Bernice; COGA Collaborators; Kuperman, Samuel; Kramer, John; Bucholz, Kathleen; Medical and Molecular Genetics, School of Medicine
    The collaborative study on the genetics of alcoholism (COGA) is a multi-site, multidisciplinary project with the goal of identifying how genes are involved in alcohol use disorder and related outcomes, and characterizing how genetic risk unfolds across development and in conjunction with the environment and brain function. COGA is a multi-generational family-based study in which probands were recruited through alcohol treatment centers, along with a set of community comparison families. Nearly 18,000 individuals from >2200 families have been assessed over a period of over 30 years with a rich phenotypic battery that includes semi-structured psychiatric interviews and questionnaire measures, along with DNA collection and electrophysiological data on a large subset. Participants range in age from 7 to 97, with many having longitudinal assessments, providing a valuable opportunity to study alcohol use and problems across the lifespan. Here we provide an overview of data collection methods for the COGA sample, and details about sample characteristics and comorbidity. We also review key research findings that have emerged from analyses of the COGA data. COGA data are available broadly to researchers, and we hope this overview will encourage further collaboration and use of these data to advance the field.