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Item Association of Cannabis Use With Nausea and Vomiting of Pregnancy(Wolters Kluwer, 2022) Metz, Torri D.; Allshouse, Amanda A.; McMillin, Gwendolyn A.; Silver, Robert M.; Smid, Marcela C.; Haas, David M.; Simhan, Hyagriv N.; Saade, George R.; Grobman, William A.; Parry, Samuel; Chung, Judith H.; Jarlenski, Marian P.; Obstetrics and Gynecology, School of MedicineOur objective was to evaluate whether cannabis use was associated with nausea and vomiting in early pregnancy. Participants from nuMoM2b (Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be) enrolled from October 2010 through September 2013 with a PUQE (Pregnancy-Unique Quantification of Emesis) questionnaire and an available stored urine sample from the first study visit (median gestational age 12 weeks) were included. Cannabis exposure was ascertained by urine immunoassay for 11-nor-9-carboxy-delta-9-tetrahydrocannabinol (THC-COOH); positive results were confirmed with liquid chromatography tandem mass spectrometry. The primary outcome was moderate-to-severe nausea by the PUQE score. Overall, 9,250 participants were included, and 5.8% (95% CI 5.4-6.3%) had detectable urine THC-COOH. In adjusted analyses, higher THC-COOH levels were associated with greater odds of moderate-to-severe nausea (20.7% in the group with THC-COOH detected vs 15.5% in the group with THC-COOH not detected, adjusted odds ratio 1.6, 95% CI 1.1-2.2 for a 500 ng/mg Cr THC-COOH increment).Item Cardiovascular pharmacology of 9-tetrahydrocannabinol(1972) Milzoff, Joel RobertItem Clinical investigations with marihuana and alcohol(1970) Manno, Joseph E.Item The combined effects of cannabichromene and delta-9-Tetrahydrocannabinol(1980) O'Neil, James DennenItem The combined effects of cannabidiol and delta-9-tetrahydrocannabinol(1974) McCoy, Daniel JosephItem The effects of delta-9-tetrahydrocannabinol and nabilone on respiratory smooth muscle(1979) Orzelek, Rita MariaItem The identification, isolation, toxicity, and tissue distribution of [delta]⁹-tetrahydrocannabinol(1970) Turk, Robert FrankItem The influence of cannabidiol on the effects of delta-9-tetrahydrocannabinol(1976) Dalton, WilliamItem Synthesis and pharmacologic investigation of some cannabinol and tetrahydrocannabinol analogs(1967) Garriott, James C.