Browsing by Subject "Dissemination"

Now showing 1 - 4 of 4
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    Cerebrospinal Fluid Drop Metastases of Canine Glioma: Magnetic Resonance Imaging Classification
    (Frontiers Media, 2021-05-03) Bentley, R. Timothy; Yanke, Amy B.; Miller, Margaret A.; Heng, Hock Gan; Cohen-Gadol, Aaron; Rossmeisl, John H.; Neurological Surgery, School of Medicine
    Dissemination of glioma in humans can occur as leptomeningeal nodules, diffuse leptomeningeal lesions, or ependymal lesions. Cerebrospinal fluid (CSF) drop metastasis of glioma is not well-recognized in dogs. Ten dogs with at least two anatomically distinct and histologically confirmed foci of glioma were included in this study. The 10 dogs underwent 28 magnetic resonance imaging (MRI) examinations, with distant CSF drop metastasis revealed in 13 MRIs. The CSF drop metastases appeared as leptomeningeal nodules in four dogs, diffuse leptomeningeal lesions in six dogs, and ependymal lesions in seven dogs; six dogs had a combination of lesion types. Primary tumors were generally T2-heterogeneous and contrast-enhancing. Many metastases were T2-homogeneous and non-enhancing. Diffuse leptomeningeal lesions were seen as widespread extra-axial contrast-enhancement, again very dissimilar to the intra-axial primary mass. Primary masses were rostrotentorial, whereas metastases generally occurred in the direction of CSF flow, in ventricles, CSF cisterns, and the central canal or leptomeninges of the cervical or thoracolumbar spinal cord. Seven of the dogs had received therapy limited to the primary mass, such as surgery or stereotactic radiation, then developed metastasis in the following months. CSF drop metastasis of glioma may take a very different appearance on MRI to the primary mass, including periventricular lesions that are more homogeneous and less contrast-enhancing, rostral horn signal changes, or leptomeningeal enhancement ventral to the brainstem or encircling the spinal cord.
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    Completing the Circle: Open Access to Translational Research and Scholarly Works
    (CUMU, 2023-09-18) Viehweg, Stephan; Odell, Jere D.; Polley, David E.; McLucas, Nouri
    IUPUI’s Center for Translating Research Into Practice (TRIP) and IUPUI University Library (Library) developed a partnership to enhance community access to faculty scholarship resulting from community-engaged and translational research. Library staff archive the scholarship of faculty affiliated with TRIP in IUPUI ScholarWorks, the campus’s open access institutional repository. The TRIP Scholarly Works Program was launched in 2013 and outcomes include benefits for faculty authors (increased readership) and for a world of readers (free access). After almost 10 years in existence, Library and TRIP staff sought to evaluate the success of this program. A survey was distributed to TRIP affiliated faculty to assess the impact of open access to their scholarship on their work as community-engaged and translational scholars. Faculty participants report a variety of benefits and yet, also indicate a need for increased program communication and fewer barriers to participation.
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    Incorporating Acupuncture Into American Healthcare: Initiating a Discussion on Implementation Science, the Status of the Field, and Stakeholder Considerations
    (Sage, 2021-08-25) Miller, David W.; Roseen, Eric J.; Stone, Jennifer A.M.; Gardiner, Paula; Olson, Juli; Rosen, Shellie; Wayne, Peter; Davis, Robert; Coeytaux, Remy; Anesthesia, School of Medicine
    Introduction: The field of implementation science is the study of methods that promote the uptake of evidence-based interventions into healthcare policy and practice. While acupuncture has gained significant traction in the American healthcare landscape, its journey has been somewhat haphazard and non-linear. Methods: In June 2019, a group of thirty diverse stakeholders was convened by the Society for Acupuncture Research with the support of a Patient Centered Outcomes Research Institute, Eugene Washington Engagement Award. This group of stakeholders represented a diverse mix of patients, providers, academicians, researchers, funders, allied health professionals, insurers, association leaders, certification experts, and military program developers. The collective engaged in discussion that explored acupuncture's status in healthcare, including reflections on its safety, effectiveness, best practices, and the actual implementation of acupuncture as seen from diverse stakeholder viewpoints. Objectives: A primary goal was to consider how to utilize knowledge from the field of implementation science more systematically and intentionally to disseminate information about acupuncture and its research base, through application of methods known to implementation science. The group also considered novel challenges that acupuncture may present to known implementation processes. Findings: This article summarizes the initial findings of this in-person meeting of stakeholders and the ongoing discussion among the subject matter experts who authored this report. The goal of this report is to catalyze greater conversation about how the field of implementation science might intersect with practice, access, research, and policymaking pertaining to acupuncture. Core concepts of implementation science and its relationship to acupuncture are introduced, and the case for acupuncture as an Evidence Based Practice (EBP) is established. The status of the field and current environment of acupuncture is examined, and the perspectives of four stakeholder groups--patients, two types of professional practitioners, and researchers--are explored in more detail.
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    Taking an HPV vaccine research-tested intervention to scale in a clinical setting
    (Oxford University Press, 2018-09-08) Hopfer, Suellen; Ray, Anne E.; Hecht, Michael L.; Miller-Day, Michelle; Belue, Rhonda; Zimet, Gregory; Evans, W. Douglas; McKee, Francis X.; Pediatrics, School of Medicine
    Research tested interventions are seldom ready for wide spread use. Successful intervention adaptation to clinical settings demands an iterative process with target audience feedback. We describe the adaptation process of implementing an NCI research tested HPV vaccine intervention, Women's Stories, to a community clinic context (Planned Parenthood). Five phases are described for the adaptation of content and the development of a health kiosk intervention delivery system: (a) informant interviews with the target audience of young adult, predominantly African-American women, (b) translating HPV vaccine decision narratives into prevention messages, (c) health kiosk interface design, (d) conducting a usability study of the health kiosk intervention product, and (e) conducting a waiting room observational study. Lessons learned and challenges in adapting prevention interventions to clinical settings are discussed.