Browsing by Subject "Crizotinib"
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Item Spotlight on the treatment of ALK-rearranged non-small-cell lung cancer.(Future Medicine, 2017-12) Mamdani, Hirva; Jalal, Shadia I.; Medicine, School of MedicineItem Targeted treatment of refractory primitive neuroectodermal tumor arising from an immature teratoma with crizotinib leading to a sustained response(Wiley, 2023-01-03) Snyder, Benjamin M.; Lion, Alex H.; Helvie, Amy E.; Marshall, Mark S.; Ferguson, Michael J.; Pediatrics, School of MedicineHere we present a case of metastatic PNET which arose from an immature teratoma that was refractory to standard Ewing sarcoma chemotherapy. This PNET was determined to have elevated levels of ALK protein via IHC. The patient was treated with crizotinib on a palliative basis with a sustained response.