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Item Epicardial Adipose Tissue and Renal Disease(MDPI, 2019-03-02) Aeddula, Narothama Reddy; Cheungpasitporn, Wisit; Thongprayoon, Charat; Pathireddy, Samata; Medicine, School of MedicineEpicardial adipose tissue (EAT) is derived from splanchnic mesoderm, localized anatomically between the myocardium and pericardial visceral layer, and surrounds the coronary arteries. Being a metabolically active organ, EAT secretes numerous cytokines, which moderate cardiovascular morphology and function. Through its paracrine and vasocrine secretions, EAT may play a prominent role in modulating cardiac function. EAT protects the heart in normal physiological conditions by secreting a variety of adipokines with anti-atherosclerotic properties, and in contrast, secretes inflammatory molecules in pathologic conditions that may play a dynamic role in the pathogenesis of cardiovascular diseases by promoting atherosclerosis. Considerable research has been focused on comparing the anatomical and biochemical features of EAT in healthy people, and a variety of disease conditions such as cardiovascular diseases and renal diseases. The global cardiovascular morbidity and mortality in renal disease are high, and there is a paucity of concrete evidence and societal guidelines to detect early cardiovascular disease (CVD) in this group of patients. Here we performed a clinical review on the existing evidence and knowledge on EAT in patients with renal disease, to evaluate its application as a reliable, early, noninvasive biomarker and indicator for CVD, and to assess its significance in cardiovascular risk stratification.Item Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension(Wolters Kluwer, 2021) Parati, Gianfranco; Stergiou, George S.; Bilo, Grzegorz; Kollias, Anastasios; Pengo, Martino; Ochoa, Juan Eugenio; Agarwal, Rajiv; Asayama, Kei; Asmar, Roland; Burnier, Michel; De La Sierra, Alejandro; Giannattasio, Cristina; Gosse, Philippe; Head, Geoffrey; Hoshide, Satoshi; Imai, Yutaka; Kario, Kazuomi; Li, Yan; Manios, Efstathios; Mant, Jonathan; McManus, Richard J.; Mengden, Thomas; Mihailidou, Anastasia S.; Muntner, Paul; Myers, Martin; Niiranen, Teemu; Ntineri, Angeliki; O'Brien, Eoin; Octavio, José Andres; Ohkubo, Takayoshi; Omboni, Stefano; Padfield, Paul; Palatini, Paolo; Pellegrini, Dario; Postel-Vinay, Nicolas; Ramirez, Agustin J.; Sharman, James E.; Shennan, Andrew; Silva, Egle; Topouchian, Jirar; Torlasco, Camilla; Wang, Ji Guang; Weber, Michael A.; Whelton, Paul K.; White, William B.; Mancia, Giuseppe; Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension; Medicine, School of MedicineThe present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including a recent statement by the American Heart association, as well as technological developments, which have occurred over the past 20 years. The present document has been developed by the same ESH Working Group with inputs from an international team of experts, and has been endorsed by the ESH.Item Home blood pressure monitoring: methodology, clinical relevance and practical application: a 2021 position paper by the Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension(Wolters Kluwer, 2021) Parati, Gianfranco; Stergiou, George S.; Bilo, Grzegorz; Kollias, Anastasios; Pengo, Martino; Ochoa, Juan Eugenio; Agarwal, Rajiv; Asayama, Kei; Asmar, Roland; Burnier, Michel; De La Sierra, Alejandro; Giannattasio, Cristina; Gosse, Philippe; Head, Geoffrey; Hoshide, Satoshi; Imai, Yutaka; Kario, Kazuomi; Li, Yan; Manios, Efstathios; Mant, Jonathan; McManus, Richard J.; Mengden, Thomas; Mihailidou, Anastasia S.; Muntner, Paul; Myers, Martin; Niiranen, Teemu; Ntineri, Angeliki; O'Brien, Eoin; Octavio, José Andres; Ohkubo, Takayoshi; Omboni, Stefano; Padfield, Paul; Palatini, Paolo; Pellegrini, Dario; Postel-Vinay, Nicolas; Ramirez, Agustin J.; Sharman, James E.; Shennan, Andrew; Silva, Egle; Topouchian, Jirar; Torlasco, Camilla; Wang, Ji Guang; Weber, Michael A.; Whelton, Paul K.; White, William B.; Mancia, Giuseppe; Working Group on Blood Pressure Monitoring and Cardiovascular Variability of the European Society of Hypertension; Medicine, School of MedicineThe present paper provides an update of previous recommendations on Home Blood Pressure Monitoring from the European Society of Hypertension (ESH) Working Group on Blood Pressure Monitoring and Cardiovascular Variability sequentially published in years 2000, 2008 and 2010. This update has taken into account new evidence in this field, including a recent statement by the American Heart association, as well as technological developments, which have occurred over the past 20 years. The present document has been developed by the same ESH Working Group with inputs from an international team of experts, and has been endorsed by the ESH.Item Red Hair Color is Associated with Elevated C-Reactive Protein Levels among U.S. Women(Elsevier, 2021) Hartman, Rebecca I.; Tang, Huilin; Hang, Dong; Song, Mingyang; Nan, Hongmei; Li, Xin; Epidemiology, School of Public Health