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Item CardioMEMS Heart Failure System: An Up-to-Date Review(Springer Nature, 2025-01-22) Tolu-Akinnawo, Oluwaremilekun; Akhtar, Naveed; Zalavadia, Nirav; Guglin, Maya; Medicine, School of MedicineHeart failure (HF) continues to represent a significant public health concern. While patients with HF with reduced ejection fraction (HFrEF) face a high risk of arrhythmias, both patients with HFrEF and HF with preserved ejection fraction (HFpEF) experience fluid overload, leading to repeated hospitalizations. Traditional monitoring methods have limited ability to manage HF exacerbations preemptively. However, the CardioMEMS™ (Abbott Laboratories, Chicago, IL) HF system, an implantable microelectromechanical sensor, has emerged as an innovative solution, enabling real-time remote monitoring of pulmonary artery pressures (PAPs). CardioMEMS has significantly reduced HF-related hospitalizations and improved patient quality of life (QOL) by facilitating early intervention before clinical symptoms. This article explores the technical specifications, clinical efficacy, integration into clinical practice, and economic impact of the CardioMEMS system. Furthermore, we discuss the challenges and limitations associated with its widespread adoption and propose considerations for future research to enhance its cost-effectiveness and accessibility in diverse healthcare settings.Item Dysfunctional Implantable Pulmonary Artery Sensor Device (CardioMEMS) in Group 2 Pulmonary Hypertension(Elsevier, 2025-01-15) Abdelkader, Abdalla Eltayeb A.; Ilonze, Onyedika J.; Guglin, Maya; Medicine, School of MedicineImplantable hemodynamic devices like the CardioMEMS HF System are commonly used to manage fluid status in patients with heart failure (HF) by measuring pulmonary pressures. Although CardioMEMS has been shown to reduce HF hospitalizations, rare complications (eg, device endothelialization) can occur and warrant clinical attention. A 67-year-old woman with HF with preserved ejection fraction and group 2 pulmonary hypertension experienced recurrent HF exacerbations. Despite optimal therapy, she was not a candidate for advanced HF therapies. The CardioMEMS device, initially effective for fluid management, showed dampened waveforms due to endothelialization, leading to reimplantation. Endothelialization is a rare but significant complication that can dampen pressure waveforms. Proper placement in vessels larger than 7 mm and careful monitoring of waveforms can help manage this issue. Device recalibration can usually address most cases; however, reimplantation may be required.