Browsing by Subject "Cancer resistance"

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    The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
    (Hindawi, 2016-12-26) Pandya, Pankita H.; Murrary, Mary E.; Pollok, Karen E.; Renbarger, Jamie L.; Department of Medicine, IU School of Medicine
    Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies.