Browsing by Subject "COVID 19"

Now showing 1 - 6 of 6
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    Accountability in clinical trial diversity: The buck stops where?
    (Elsevier, 2021-06-01) Nephew, Lauren D.; Medicine, School of Medicine
    If the Pfizer and Moderna Coronavirus Disease (COVID-19) studies taught us one thing, it is that clinical trials can better reflect the diverse demographics of the population. Why then, do not most other Phase 3 clinical trials account for the diversity of the population who will most likely use the drug? Most do not, because there is no accountability. In developing the COVID-19 vaccine, industry and its partners were well aware of their mandate: develop a vaccine quickly that would be acceptable and legitimate to the public.
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    An Accountable Care Organization Maintains Access for Appendicitis During the COVID-19 Pandemic
    (Elsevier, 2023) Menchaca, Alicia D.; Style, Candace C.; Wang, Ling; Cooper, Jennifer N.; Minneci, Peter C.; Olutoye, Oluyinka O.; Surgery, School of Medicine
    Introduction: It has been reported that pediatric patients experienced a delay in treatment for acute appendicitis during the pandemic, resulting in increased rates of complicated appendicitis. We investigated the association of the COVID-19 pandemic and the incidence and severity of acute appendicitis among pediatric Medicaid patients using a population-based approach. Methods: The claims database of Partners For Kids, a pediatric Medicaid accountable care organization (ACO) in Ohio, was queried for cases of acute appendicitis from April to August 2017-2020. The monthly rate of acute appendicitis/100,000 covered lives was calculated each year and compared over time. Rates of complicated appendicitis were also compared. Diagnosis code validation for classification as complicated or uncomplicated appendicitis was performed for patients treated at our hospital. Results: During the study period, 465 unique cases of acute appendicitis were identified. Forty percent (186/465) were coded as complicated. No significant difference in the incidence of acute appendicitis cases was observed across the 4 y, either in an overall comparison or in pairwise comparisons (P > 0.15 for all). The proportion of acute appendicitis cases that were coded as complicated did vary significantly over the 4-year study period (P = 0.005); this was due to this proportion being significantly higher in 2018 than in either 2019 (P = 0.005 versus 2018) or 2020 (P = 0.03 versus 2018). Conclusions: The COVID-19 pandemic was not associated with reduced access to treatment for acute appendicitis among patients in a pediatric Medicaid ACO. This suggests that an ACO may promote continued healthcare access for their covered population during an unexpected crisis.
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    COVID-19 and clinical pharmacy worldwide—A wake up call and a call to action
    (Wiley, 2020-06-15) Cheong, Mark Wing Loong; Brock, Tina; Karwa, Rakhi; Pastakia, Sonak D.; Medicine, School of Medicine
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    Life after plague
    (Springer, 2020-05-30) Gunderman, Richard B.; Pediatrics, School of Medicine
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    Molecular diagnosis and therapy for Plasmodium ovale infection of a returned traveler from East Africa
    (Elsevier, 2021-05-06) Tseng, Yu-Chuan; Chang, Yu-Chang; Lee, Chihyi; Hsu, Shih-Fen; Chang, Pai-Chuan; Hsu, Jen-Jen; Lin, Peter Bor-Chian; Lu, Min-Chi; Tien, Ni; Hsiao, Chiung-Tzu; Medicine, School of Medicine
    Malaria is an infectious disease caused by Plasmodium parasites that are mainly transmitted through the bites of infected female Anopheles mosquitoes. The average annual number of malaria cases was less than ten in Taiwan in the last five years. Most of the cases were caused by Plasmodium vivax and Plasmodium falciparum, and were primarily diagnosed in travelers who returned from Southeast Asia and Africa. Here, we report the first case of Plasmodium ovale infection within five years that was confirmed by peripheral blood smear examination and molecular identification in a 25-year-old Asian female patient who returned from Uganda.
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    Multimodality Cardiovascular Imaging in the Midst of the COVID-19 Pandemic: Ramping Up Safely to a New Normal
    (Elsevier, 2020-07-07) Zoghbi, William A.; DiCarli, Marcelo F.; Blankstein, Ron; Choi, Andrew D.; Dilsizian, Vasken; Flachskampf, Frank A.; Geske, Jeffrey B.; Grayburn, Paul A.; Jaffer, Farouc A.; Kwong, Raymond Y.; Leipsic, Jonathan A.; Marwick, Thomas H.; Nagel, Eike; Nieman, Koen; Raman, Subha V.; Salerno, Michael; Sengupta, Partho P.; Shaw, Leslee J.; Chandrashekhar, Y. S.; ACC Imaging Council; Medicine, School of Medicine