Browsing by Subject "Brain dysfunction"

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    Effects of music intervention on inflammatory markers in critically ill and post-operative patients: A systematic review of the literature
    (Elsevier, 2018) Khan, Sikandar H.; Kitsis, Michelle; Golovyan, Dmitriy; Wang, Sophia; Chlan, Linda L.; Boustani, Malaz; Khan, Babar A.; Medicine, School of Medicine
    BACKGROUND: Music listening has been shown to reduce anxiety, stress, and patient tolerance of procedures. Music may also have beneficial effects on inflammatory biomarkers in intensive care and post-operative patients, but the quality of evidence is not clear. OBJECTIVES: We conducted a systematic review to evaluate the effects of music on inflammatory biomarkers in intensive care, and post-operative patients. METHODS: A comprehensive search of the literature was performed. After screening 1570 references, full text review of 26 studies was performed. Fourteen studies were selected for inclusion. RESULTS: Seven studies showed a significant decrease in cortisol levels, but the level of evidence was low. Three studies had low risk of methodological bias, while 11 studies had high risk of bias. CONCLUSIONS: Music intervention may decrease cortisol levels, but other biomarkers remain unchanged. Given the low level of evidence, further research on music effects on inflammatory biomarkers is needed.