Browsing by Subject "Asymptomatic"

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    COVID-19 Home Monitoring Program: Healthcare Innovation in developing, maintaining, and Outcome of SARS-CoV-2 infected patients
    (Elsevier, 2021-09) Al-Tawfiq, Jaffar A.; Kheir, Hatim; Al-Dakheel, Talal; Al-Qahtani, Saeed; AlKhadra, Hussain; Sarhan, Ahlam; Halaiga, Maryam Bu; Ibrahim, Rana; Medicine, School of Medicine
    Introduction The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) had caused an increased burden on healthcare organizations. Thus, a new strategy is needed to ensure all COVID-19 positive cases are followed up appropriately, receive the proper medical and psychological support, and comply with the isolation guidelines. Here, we describe the characteristics and outcome of COVID-19 patients who were managed at home. In addition, we describe the differences between asymptomatic and those with mild symptoms. Materials and Methods This is descriptive study of all COVID-19 positive cases who were monitored utilizing the home care concept. Results During the study period from June 8 to October 18, 2020, there were a total of 5368 COVID-19 patients who were referred to the home isolation/monitoring program. Of those, 2397 (45%) were female and 2971 (55%) were male. Of the total cases, 295 (5%) required hospital admission, 45 (1%) were admitted to zone 2, and the majority 5028 (94%) were continued in the home monitoring till recovery. Of the total cases, 3137 (59%) were asymptomatic and the remaining 41% were symptomatic. Asymptomatic patients in comparison to symptomatic patients showed significant differences in relation to age, gender, being healthcare workers, and the presence of significant medical conditions. However, a logistic regression analysis showed that only age and the presence of diabetes mellitus were associated with the presence of symptoms. The mean age (+ SD) of those who required hospital admission was higher than those who were discharged or cared for in zone 2. Conclusion The utilization of home monitoring program was effective and safe in patients who were either asymptomatic or had mild symptoms.
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    Prevalence of Asymptomatic SARS-CoV-2 Infection in Children and Adults in Marion County, Indiana
    (Cureus Inc., 2020-08-16) Wood, James; Datta, Dibyadyuti; Hudson, Brenda L; Co, Katrina; Tepner, Sarah; Hardwick, Emily; John, Chandy C.; Pediatrics, School of Medicine
    Background and Objectives: Two community studies outside the US showed asymptomatic infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in adults, but not in children <10 years of age. In this study, we assessed the prevalence of asymptomatic SARS-CoV-2 infection in children and adults in Marion County, Indiana. Methods: Individuals living in Marion County with no symptoms of coronavirus 2019 disease (COVID-19) within seven days of enrollment were eligible for this cross-sectional household study. Study kits were delivered to the participant’s residence for self-swabbing, picked up by the study team, and tested by polymerase chain reaction (PCR) for SAR-CoV-2 infection. Results: Five hundred eleven nasal swabs were collected from 119 children and 392 adults ≥18 years of age. One participant (seven years of age) tested positive, for an overall study prevalence of 0.2% (95% CI 0, 0.6%). The participant had no known contact with a person with SARS-CoV-2 infection, and five family members tested negative for infection. The child and family members all tested negative for infection 10 and 20 days after the first test, and none developed symptoms of COVID-19 for 20 days after testing. Conclusions: Asymptomatic SARS-CoV-2 infection can occur in children <10 years with no known COVID-19 exposure. Large cohort studies should be conducted to determine prevalence of asymptomatic infection and risk of transmission from asymptomatic infection in children and adults over time.