Browsing by Subject "Anatomy"

Now showing 1 - 10 of 30
  • Thumbnail Image
    Item
    Anatomy Nights: An international public engagement event increases audience knowledge of brain anatomy
    (PLOS, 2022-06-09) Sanders, Katherine A.; Philp, Janet A.C.; Jordan, Crispin Y.; Cale, Andrew S.; Cunningham, Claire L.; Organ, Jason M.; Anatomy, Cell Biology and Physiology, School of Medicine
    Anatomy Nights is an international public engagement event created to bring anatomy and anatomists back to public spaces with the goal of increasing the public's understanding of their own anatomy by comparison with non-human tissues. The event consists of a 30-minute mini-lecture on the anatomy of a specific anatomical organ followed by a dissection of animal tissues to demonstrate the same organ anatomy. Before and after the lecture and dissection, participants complete research surveys designed to assess prior knowledge and knowledge gained as a result of participation in the event, respectively. This study reports the results of Anatomy Nights brain events held at four different venues in the UK and USA in 2018 and 2019. Two general questions were asked of the data: 1) Do participant post-event test scores differ from pre-event scores; and 2) Are there differences in participant scores based on location, educational background, and career. We addressed these questions using a combination of generalized linear models (R's glm function; R version 4.1.0 [R Core Team, 2014]) that assumed a binomial distribution and implemented a logit link function, as well as likelihood estimates to compare models. Survey data from 91 participants indicate that scores improve on post-event tests compared to pre-event tests, and these results hold irrespective of location, educational background, and career. In the pre-event tests, participants performed well on naming structures with an English name (frontal lobe and brainstem), and showed signs of improvement on other anatomical names in the post-test. Despite this improvement in knowledge, we found no evidence that participation in Anatomy Nights improved participants' ability to apply this knowledge to neuroanatomical contexts (e.g., stroke).
  • Thumbnail Image
    Item
    Build-A-Pelvis: a Low-cost Modeling Activity to Improve Medical Students’ Understanding of Perineal Anatomy
    (Springer, 2019-07-26) Smith, Theodore C.; Husmann, Polly; Medicine, School of Medicine
    Background: We demonstrate a low-cost, active learning module that provides medical students with a three-dimensional understanding of perineal anatomy. Activity: Student groups completed a perineal model and then reviewed another group's model of the opposite sex. Multiple pre- and post-module quizzes and correlated exam questions were analyzed. Self-reported understanding of perineal anatomy and usefulness of activity were reported. Results: Students showed significant increases between pre- and post-quiz scores and perceptions of understanding (p < 0.001). Outcomes on exam questions were significantly higher than non-participating counterparts (p = 0.011). Discussion: Thus, this low-cost modeling activity can benefit learning of perineal anatomy.
  • Thumbnail Image
    Item
    CHAPTER 12 - Non-neoplastic diseases of the testis
    (Elsevier, 2020-06-22) Nistal, Manuel; Paniagua, Ricardo; Bostwick, David G.; Cheng, Liang; Pathology and Laboratory Medicine, School of Medicine
  • Thumbnail Image
    Item
    Congenital anatomic variations in a pancreas allograft: Is this consistent with safe transplant?
    (Elsevier, 2022) Walia, Sonal; Powelson, John A.; Lutz, Andrew J.; Fridell, Jonathan A.; Surgery, School of Medicine
  • Thumbnail Image
    Item
    Effects of donor-specific microvascular anatomy on hemodynamic perfusion in human choriocapillaris
    (Springer Nature, 2023-12-19) An, Senyou; Yu, Huidan; Islam, MD Mahfuzul; Zhang, Xiaoyu; Zhan, Yuting; Olivieri, Joseph J.; Ambati, Jayakrishna; Yao, Jun; Gelfand, Bradley D.; Mechanical and Energy Engineering, Purdue School of Engineering and Technology
    Evidence from histopathology and clinical imaging suggest that choroidal anatomy and hemodynamic perfusion are among the earliest changes in retinal diseases such as age-related macular degeneration (AMD). However, how inner choroidal anatomy affects hemodynamic perfusion is not well understood. Therefore, we sought to understand the influences of choroidal microvascular architecture on the spatial distribution of hemodynamic parameters in choriocapillaris from human donor eyes using image-based computational hemodynamic (ICH) simulations. We subjected image-based inner choroid reconstructions from eight human donor eyes to ICH simulation using a kinetic-based volumetric lattice Boltzmann method to compute hemodynamic distributions of velocity, pressure, and endothelial shear stress. Here, we demonstrate that anatomic parameters, including arteriolar and venular arrangements and intercapillary pillar density and distribution exert profound influences on inner choroidal hemodynamic characteristics. Reductions in capillary, arteriolar, and venular density not only reduce the overall blood velocity within choriocapillaris, but also substantially increase its spatial heterogeneity. These first-ever findings improve understanding of how choroidal anatomy affects hemodynamics and may contribute to pathogenesis of retinal diseases such as AMD.
  • Thumbnail Image
    Item
    Efficacy of Novel Bracing for Treating Sciatica and Cadaveric Dissection to Examine Excursion of the Sciatic Nerve
    (2023-07-28) Callahan, Kyle; Dellacqua, Dale
    Background/Objective: Sciatica affects nearly half of all Americans and can often become debilitating, leading to severe pain that can limit performing activities of daily living. Brace application has not been tried for alleviation of pain. In this study, we seek to find if a novel brace can decrease pain and decrease bothersome level of symptoms for those suffering from sciatica. In addition, this study utilizes a cadaveric dissection to understand how the sciatic nerve stretches and tensions upon lower limb manipulation. Methods: Fourteen patients self-reported pain, functionality, and bothersome levels pre- and post-bracing. Excel’s data analysis tool was utilized to run statistical tests. One cadaver (2 lower limbs) was dissected, revealing the sciatic nerve at the hip and knee, while tibial nerve at the ankle. Excursion was measured utilizing a fixed pin and an initial distance, the leg manipulated, and final distance from pin measured. Ultimately, excursion was deemed final distance minus initial distance from the pin. Results: The brace decreases Visual Analogue Scale (VAS) scores, increases Patient Reported Outcomes, and decreases Sciatica Bothersome Indexes. There was a significant difference in VAS pre- versus post-brace values at initial and 7-day post-visit but not at 21- or 42-day post-visit. Sciatic nerve excursion was greatest at the ankle. Discussion/Conclusion Brace use decreases pain levels, increases functionality, and decreases bothersome level of symptoms. The distal nerve moves more upon manipulation and therefore is more prone to tensioning than the proximal nerve. Dissection data illustrates how the brace positions the limb in a way that promotes “detensioning” of the nerve, alleviating sciatica. More cadaver data is needed. Presentation recording available online: https://purl.dlib.indiana.edu/iudl/media/c58059kh24
  • Thumbnail Image
    Item
    External cortical landmarks and measurements for the temporal horn: Anatomic study with application to surgery of the temporal lobe
    (Wolters Kluwer, 2015-02-03) Tubbs, R. Shane; Sharma, Amit; Loukas, Marios; Cohen-Gadol, Aaron; Department of Neurological Surgery, IU School of Medicine
    BACKGROUND: The location of the temporal horn is important to neurosurgeons during procedures such as amygdalohippocampectomy and intraventricular electrode placement for temporal lobe seizure monitoring. However, sometimes the temporal horn is difficult to localize, especially without neuronavigation. The authors aimed to better localize this structure using superficial anatomic landmarks. METHODS: Twenty-two brain halves were dissected from the midline, and the fornix identified and followed toward the left and right temporal horns. Once the temporal horn was isolated from a mesial approach, 6-cm long needles were placed into its anterior and posterior walls of the temporal horn and passed laterally from the axial plane to the cortical surface. Pin exit sites were marked externally and measurements taken between the outer temporal lobe cortex and the underlying temporal horn. RESULTS: No statistical differences were noted between left and right sides. The temporal horn was generally directed anteroinferiorly and best marked externally by the inferior temporal sulcus. The mean length of the temporal horn was 4.4 cm. Mean distance from anterior temporal tip to anterior wall of the temporal horn was 3.3 cm. The mean distance from the anterior temporal tip to the posterior wall of the temporal horn was 7 cm. The anterior wall of the temporal horn was a mean of 3 mm superior to the inferior temporal sulcus. The posterior wall was a mean of 1.2 cm superior to the inferior temporal sulcus. CONCLUSIONS: These landmarks and measurements may help neurosurgeons better localize this part of the lateral ventricular system.
  • Thumbnail Image
    Item
    External cortical landmarks for localization of the hippocampus: Application for temporal lobectomy and amygdalohippocampectomy
    (Scientific Scholar, 2018-08-22) Tubbs, R. Shane; Loukas, Marios; Barbaro, Nicholas M.; Shah, Kushal J.; Cohen-Gadol, Aaron A.; Neurological Surgery, School of Medicine
    Background: Accessing the hippocampus for amygdalohippocampectomy and minimally invasive procedures, such as depth electrode placement, require an accurate knowledge regarding the location of the hippocampus. Methods: The authors removed 10 human cadaveric brains from the cranium and observed the relationships between the lateral temporal neocortex and the underlying hippocampus. They then measured the distance between the hippocampus and superficial landmarks. The authors also validated their study using magnetic resonance imaging (MRI) scans of 10 patients suffering from medial temporal lobe sclerosis where the distance from the hippocampal head to the anterior temporal tip was measured. Results: In general, the length of the hippocampus was along the inferior temporal sulcus and inferior aspect of the middle temporal gyrus. Although the hippocampus tended to be more superiorly located in female specimens and on the left side, this did not reach statistical significance. The length of the hippocampus tended to be shorter in females, but this too failed to reach statistical significance. The mean distance from the anterior temporal tip to the hippocampal head was identical in the cadavers and MRIs of patients with medial temporal lobe sclerosis. Conclusions: Additional landmarks for localizing the underlying hippocampus may be helpful in temporal lobe surgery. Based on this study, there are relatively constant anatomical landmarks between the hippocampus and overlying temporal cortex. Such landmarks may be used in localizing the hippocampus during amygdalohippocampectomy and depth electrode implantation in verifying the accuracy of image-guided methods and as adjuvant methodologies when these latter technologies are not used or are unavailable.
  • Thumbnail Image
    Item
    From pyramids to columns: the structure of the kidney
    (ASCP, 2012) Wood, Debra M.
  • Thumbnail Image
    Item
    The Impact of Medical Education Reform on the Teaching and Learning of the Anatomical Sciences
    (2019-06) Taylor, Melissa Anne; O'Laughlin, Valerie Dean; Brokaw, James; Husmann, Polly; Lester, Jessica
    Curricular reform in medical education is a process that has been ongoing for quite some time. Major revision of medical curricula has been occurring since the early eighteenth century. In recent decades, curricular reform has had a monumental impact on the anatomical science subjects. This research investigated how specifically the anatomical science disciplines were impacted by curricular reform at various allopathic medical schools within the United States. The goal of this research was to discover curricular variations in medical schools and to examine the perceptions of those curricular programs by faculty and students alike. Four research questions were addressed to explore the role of curricular reform in medical education using a mixed methods study design. Medical curricular websites were qualitatively analyzed to discover common trends used to describe medical curricula and content organization. Perceptions about the medical curriculum were gathered through surveys and interviews of anatomical science faculty across the country and first year medical students at Indiana University School of Medicine-Bloomington. Finally, a case study of curricular changes at Indiana University School of Medicine was documented. Results from this research demonstrated that curricular reform has had a major impact on the anatomical disciplines. Didactic lectures have been supplemented or replaced by non-didactic teaching tools. Hours dedicated to the teaching of the anatomical sciences have greatly decreased, and most anatomical disciplines are no longer taught as stand-alone courses. Qualitative results discovered that there is an overall administrative control of the medical curriculum. Additional perceptual data demonstrated the need for measuring student success past the licensing exam scores. There’s a need for future studies to further analyze student success regarding lifelong learning, problem-solving, and critical thinking skills.