Browsing by Subject "AAA"

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    Area Agency on Aging and Occupational Therapy
    (2021-05-07) Minnich, Victoria; DeRolf, Annie; Department of Occupational Therapy, School of Health and Human Sciences; Ziegler, Dustin; Stinson, Kelsey
    Area Agencies on Aging (AAAs) and the profession of occupational therapy have similar values as they pertain to the promotion of aging in place amongst community-dwelling older adults. AAAs provide a wide range of services that allow older adults to safely and productively age in their own homes rather than in institutionalized settings (National Association of Area Agencies on Aging [n4a], n.d.). Occupational therapy practitioners have an essential role in promoting quality of life, health, and participation in meaningful occupations amongst community-dwelling older adults (American Occupational Therapy Association [AOTA], 2016). Despite these similar values, there are few partnerships between the two entities as fewer than 3.2% of occupational therapists even work in community settings with older adults (AOTA, 2020b). The goal of this capstone project was to evaluate an Area Agency on Aging (AAA) and provide the organization with an evidence-based, client-centered proposal on how a staffed occupational therapy practitioner could fit within their organization. Outcomes of this capstone project consisted of five tailored recommendations for the organization as well as an increase in knowledge and perception of the scope of occupational therapy amongst the organization’s staff. Future research should be conducted on the outcomes associated with partnerships between AAAs and occupational therapy practitioners.
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    Progressive alterations in microstructural organization and biomechanical response in the ApoE mouse model of aneurysm
    (Taylor & Francis, 2013) Haskett, Darren; Azhar, Mohamad; Utzinger, Urs; Vande Geest, Jonathan P.; Pediatrics, School of Medicine
    AAA is a complex disease that leads to a localized dilation of the infrarenal aorta that develops over years. Longitudinal information in humans has been difficult to obtain for this disease, therefore mouse models have become increasingly used to study the development of AAAs. The objective of this study was to determine any changes that occur in the biomechanical response and fiber microstructure in the ApoE(-/-) AngII mouse model of aneurysm during disease progression. Adult ApoE(-/-) AngII infused mice along with wild-type controls were taken at 14 and 28 d. Aortas were excised and tested simultaneously for biaxial mechanical response and ECM organization. Data sets were fit to a Fung-type constitutive model to give peak strains and stiffness values. Images from two photon microscopy were quantified in order to assess the preferred fiber alignment and degree of fiber orientation. Biomechanical results found significant differences that were present at 14 d had returned to normal by 28 d along with significant changes in fiber orientation and dispersion indicating remodeling occurring within the aneurysmal wall. This return of some of the normal biomechanical function, in addition the continuing changes that occur in the microstructure suggest a restorative response that occurs in the ApoE(-/-) AngII infused model after the initial aneurysm formation.