Browsing by Author "Ziogas, Ioannis A."

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    Building an international network of young surgeons across surgical specialties - Introducing the Young Surgeons Publications Committee
    (Elsevier, 2025-02-14) Bolm, Louisa; Nebbia, Martina; Stoop, Thomas F.; Goetz, Mara R.; Conradi, Lena; Raschzok, Nathanael; Jansson, Hannes; Larsson, Patrik; Gerber, Sarah; Roldàn, Jorge; Michelakos, Theodoros; Winkel, Meike Ten; Kinny-Köster, Benedict; Rompen, Ingmar F.; Franklin, Oskar; Ziogas, Ioannis A.; Ishida, Hiroyuki; Khomiak, Andrii; Hashimoto, Daisuke; Groot, Vincent P.; Wu, Y. H. Andrew; Sugawara, Toshitaka; Oba, Atsushi; Maekawa, Aya; Oor, Jelmer E.; Morandi, Alessio; Stewart, David B.; Zyromski, Nicholas Joseph; Surgery, School of Medicine
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    Surgical Outcomes in Syndromic Tetralogy of Fallot: A Systematic Review and Evidence Quality Assessment
    (Springer, 2019-08) Athanasiadis, Dimitrios I.; Mylonas, Konstantinos S.; Kasparian, Karampet; Ziogas, Ioannis A.; Vlachopoulou, Dimitra; Sfyridis, Panagiotis G.; Schizas, Dimitrios; Spartalis, Eleftherios; Nikiteas, Nikolaos; Hemmati, Pouya; Kalangos, Afksendiyos; Avgerinos, Dimitrios V.; Surgery, School of Medicine
    Tetralogy of Fallot (ToF) is one of the most common cyanotic congenital heart defects. We sought to summarize all available data regarding the epidemiology and perioperative outcomes of syndromic ToF patients. A PRISMA-compliant systematic literature review of PubMed and Cochrane Library was performed. Twelve original studies were included. The incidence of syndromic ToF was 15.3% (n = 549/3597). The most prevalent genetic syndromes were 22q11.2 deletion (47.8%; 95% CI 43.4–52.2) and trisomy 21 (41.9%; 95% CI 37.7–46.3). Complete surgical repair was performed in 75.2% of the patients (n = 161/214; 95% CI 69.0–80.1) and staged repair in 24.8% (n = 53/214; 95 CI 19.4–30.9). Relief of RVOT obstruction was performed with transannular patch in 64.7% (n = 79/122; 95% CI 55.9–72.7) of the patients, pulmonary valve-sparing technique in 17.2% (n = 21/122; 95% CI 11.5–24.9), and RV-PA conduit in 18.0% (n = 22/122; 95% CI 12.1–25.9). Pleural effusions were the most common postoperative complications (n = 28/549; 5.1%; 95% CI 3.5–7.3). Reoperations were performed in 4.4% (n = 24/549; 95% CI 2.9–6.4) of the patients. All-cause mortality rate was 9.8% (n = 51/521; 95% CI 7.5–12.7). Genetic syndromes are seen in approximately 15% of ToF patients. Long-term survival exceeds 90%, suggesting that surgical management should be dictated by anatomy regardless of genetics.