Browsing by Author "Weaver, Lindsay M."

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    COVID-19-Associated Bifacial Weakness with Paresthesia Subtype of Guillain-Barré Syndrome
    (American Society of Neuroradiology, 2020-06-25) Hutchins, Katherine L.; Jansen, Jaclyn H.; Comer, Adam D.; Scheer, Richard V.; Zahn, Gregory S.; Capps, Alisha E.; Weaver, Lindsay M.; Koontz, Nicholas A.; Neurology, School of Medicine
    We report a case of bifacial weakness with paresthesia, a recognized Guillain-Barré syndrome subtype characterized by rapidly progressive facial weakness and paresthesia without ataxia or other cranial neuropathies, which was temporally associated with antecedent coronavirus 2019 (COVID-19). This case highlights a potentially novel but critically important neurologic association of the COVID-19 disease process. Herein, we detail the clinicoradiologic work-up and diagnosis, clinical course, and multidisciplinary medical management of this patient with COVID-19. This case is illustrative of the increasingly recognized but potentially underreported neurologic manifestations of COVID-19, which must be considered and further investigated in this pandemic disease.
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    Effectiveness of SBIRT for Alcohol Use Disorders in the Emergency Department: A Systematic Review
    (eScholarship Publishing, University of California, 2017-10) Barata, Isabel A.; Shandro, Jamie R.; Montgomery, Margaret; Polansky, Robin; Sachs, Carolyn J.; Duber, Herbert C.; Weaver, Lindsay M.; Heins, Alan; Owen, Heather S.; Josephson, Elaine B.; Macias-Konstantopoulos, Wendy; Emergency Medicine, School of Medicine
    Introduction Alcohol use disorders (AUD) place a significant burden on individuals and society. The emergency department (ED) offers a unique opportunity to address AUD with brief screening tools and early intervention. We undertook a systematic review of the effectiveness of ED brief interventions for patients identified through screening who are at risk for AUD, and the effectiveness of these interventions at reducing alcohol intake and preventing alcohol-related injuries. Methods We conducted systematic electronic database searches to include randomized controlled trials of AUD screening, brief intervention, referral, and treatment (SBIRT), from January 1966 to April 2016. Two authors graded and abstracted data from each included paper. Results We found 35 articles that had direct relevance to the ED with enrolled patients ranging from 12 to 70 years of age. Multiple alcohol screening tools were used to identify patients at risk for AUD. Brief intervention (BI) and brief motivational intervention (BMI) strategies were compared to a control intervention or usual care. Thirteen studies enrolling a total of 5,261 participants reported significant differences between control and intervention groups in their main alcohol-outcome criteria of number of drink days and number of units per drink day. Sixteen studies showed a reduction of alcohol consumption in both the control and intervention groups; of those, seven studies did not identify a significant intervention effect for the main outcome criteria, but nine observed some significant differences between BI and control conditions for specific subgroups (i.e., adolescents and adolescents with prior history of drinking and driving; women 22 years old or younger; low or moderate drinkers); or secondary outcome criteria (e.g. reduction in driving while intoxicated). Conclusion Moderate-quality evidence of targeted use of BI/BMI in the ED showed a small reduction in alcohol use in low or moderate drinkers, a reduction in the negative consequences of use (such as injury), and a decline in ED repeat visits for adults and children 12 years of age and older. BI delivered in the ED appears to have a short-term effect in reducing at-risk drinking.