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Browsing by Author "Subramanian, Ramesh"
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Item Access to Knowledge in India: New Research on Intellectual Property, Innovation and Development(Bloomsbury Academic, 2011) Subramanian, Ramesh; Shaver, LeaThis is the third volume in our Access to Knowledge series. India is a $1 trillion economy which nevertheless struggles with a very high poverty rate and very low access to knowledge for almost seventy percent of its population which lives in rural areas. This volume features four parts on current issues facing intellectual property, development policy (especially rural development policy) and associated innovation, from the Indian perspective. Each chapter is authored by scholars taking an interdisciplinary approach and affiliated to Indian or American universities and Indian think-tanks. Each examines a policy area that significantly impacts access to knowledge. These include information and communications technology for development; the Indian digital divide; networking rural areas; copyright and comparative business models in music; free and open source software; patent reform and access to medicines; the role of the Indian government in promoting access to knowledge internationally and domestically.Item Reperfused Myocardial Infarction: The Road to CCS Classification of Acute MI and Beyond(Elsevier, 2025) Dharmakumar, Rohan; Kloner, Robert A.; Fishbein, Michael; Heusch, Gerd; Vora, Keyur P.; Gropler, Robert; Henry, Timothy; Shing-Chan, Fai; Singh, Dhirendra; Jambunathan, Nithya; Subramanian, Ramesh; Kreutz, Rolf P.; Reed, Grant W.; Kovacs, Richard J.; Fry, Edward; Kalra, Ankur; Kumar, Andreas; Raman, Subha V.; Medicine, School of MedicineThe Canadian Cardiovascular Society recently put forth a new classification of acute reperfused myocardial infarction (MI) based on stages of myocardial injury. Backed by more than 5 decades of intense investigation in the field, the key message of this new classification is that not all MIs are the same and that the type and extent of myocardial injury should be considered in diagnosing and treating MI. We review the literature with the goal of highlighting the progressive advances that enabled the synthesis of the Canadian Cardiovascular Society classification into 4 distinct stages of tissue injury. We emphasize the major breakthroughs from insights gained from experimental, translational, and clinical studies to date. We also identify current gaps in knowledge and critical research directions that need to be pursued to improve patient care and reduce post-MI complications such as chronic heart failure and malignant arrhythmias, whose risk is linked to stage and extent of myocardial injury.