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Browsing by Author "Scanlon, Michael Lawrence"
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Item Validation of a Short Adherence Questionnaire for Children Living with HIV on Antiretroviral Therapy in Kenya(SAGE Publications, 2018-01-01) Vreeman, Rachel Christine; Scanlon, Michael Lawrence; Tu, Wanzhu; Slaven, James; Ayaya, Samuel; Nyandiko, Winstone; Pediatrics, School of MedicineBackground:There are few validated tools to measure adherence for children living with HIV. We identified questionnaire items for caregivers of Kenyan children aged <15 years living with HIV.Methods:Caregiver?child dyads were followed for 6 months. At monthly visits, the child?s HIV provider administered a 10-item questionnaire to the caregiver. Children were given electronic dose monitors (Medication Event Monitoring Systems [MEMS]). Correlation between questionnaire items and dichotomized MEMS adherence (≥90% doses taken versus <90%) was investigated using logistic regression models.Results:In 95 caregiver?child dyads, mean age of children (40% female) was 8.3 years. Items associated with higher odds of MEMS adherence in multivariable analysis included the father giving the child medication, being enrolled in a nutrition program, and the caregiver reporting no difficulties giving the child medication.Conclusion:Providers typically ask about missed doses, but asking about caregiver responsibilities and difficulties in giving the child medication may better detect suboptimal adherence.Item Validation of an HIV/AIDS Stigma Measure for Children Living with HIV and Their Families(SAGE Publications, 2019-01-01) Vreeman, Rachel Christine; Scanlon, Michael Lawrence; Tu, Wanzhu; Slaven, James; McAteer, Carole; Aluoch, Josephine; Ayaya, Samuel; Nyandiko, Winstone Mokaya; Biostatistics, School of Public HealthBackground: There are few validated tools to measure stigma, particularly among children living with HIV and their families. Methods: This study was nested within a larger study that followed 240 child–caregiver dyads (children aged 10-15 years) at 8 clinics in western Kenya. The stigma instrument was administered to all child–caregiver dyads at 2 time points 6 months apart. The primary end point was to construct validity assessed by comparison to criterion constructs using generalized estimating equation models. Results: Mean age of child participants was 12.3 years and 52% were female. Generally, caregivers reported experiencing higher levels of HIV stigma compared to their children. Children (9%) and caregivers (14%) reported that HIV stigma made them feel stressed, anxious, and depressed. Child and caregiver stigma items showed high construct validity by emotional and behavioral outcomes. Conclusions: The stigma instrument showed high validity when compared to emotional and behavioral outcomes.