Browsing by Author "Pavelka, Matthew M."

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    Potential Dextromethorphan-Induced Serotonin Syndrome Leading to Homicide and Suicide
    (Sage, 2024-01-30) Pavelka, Matthew M.; Kohr, Roland; Medicine, School of Medicine
    Limited case reports have been published regarding serotonin syndrome due to the combined effects of supratherapeutic levels of dextromethorphan and selective serotonin reuptake inhibitor. We report a case of an adolescent with postmortem findings suggestive of a diagnosis of serotonin syndrome-induced psychosis associated with a double homicide and suicide. Postmortem toxicology of the suicide victim was remarkable for elevated serotonergic metabolites of fluoxetine and dextromethorphan in a 14-year-old male.