Browsing by Author "Lo, Simon S."
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Item Commentary: Fractionated Proton Beam Radiation Therapy and Hearing Preservation for Vestibular Schwannoma: Preliminary Analysis of a Prospective Phase 2 Clinical Trial(Wolters Kluwer, 2022-07) McClelland, Shearwood; Combs, Stephanie E.; Halasz, Lia M.; Lo, Simon S.; Shiue, Kevin; Radiation Oncology, School of MedicineItem Does Graded Prognostic Assessment outperform Recursive Partitioning Analysis in patients with moderate prognosis brain metastases?(Future Medicine, 2016) Estabrook, Neil C.; Lutz, Stephen T.; Johnson, Cynthia S.; Lo, Simon S.; Henderson, Mark A.; Radiation Oncology, School of MedicineAIM: To compare the clinical utility of the Recursive Partitioning Analysis (RPA) and Graded Prognostic Assessment (GPA) in predicting outcomes for moderate prognosis patients with brain metastases. METHODS & MATERIALS: We reviewed 101 whole brain radiotherapy cases. RPA and GPA were calculated. Overall survival was compared. RESULTS: Sixty-eight patients had moderate prognosis. RPA patient characteristics for increased death hazard were ≤10 WBRT fractions or no surgery/radiosurgery. GPA patients had increased death risk with no surgery/radiosurgery or lower Karnofsky Performance Status. CONCLUSION: The indices have similar predicted survival. Patients scored by RPA with longer radiation schedules had longer survival; patients scored by GPA did not. This indicates GPA is more clinically useful, leaving less room for subjective treatment choices.Item Modern approaches to the management of brain metastases: embracing a multi-modal paradigm(AME, 2022) Vellayappan, Balamurugan; Knisely, Jonathan P. S.; Lo, Simon S.; Shiue, Kevin; Radiation Oncology, School of Medicine