Browsing by Author "Lipori, Gigi"

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    Spirometry use in patientswith sickle cell disease with and without asthma and acute chest syndrome: Amulticenter study
    (Wiley, 2020-07) Duckworth, Laurie; Black, Lucien Vandy; Ezmigna, Dima; Green, Jeanette; Yao, Yingwei; Grannis, Shaun; Klann, Jeff; Applegate, Reuben; Lipori, Gigi; Wallace, Tanya; Wilkie, Diana J.; Medicine, School of Medicine
    A de‐identified data repository of electronic medical record data, i2b2 (Informatics for Integrating Biology and the Bedside), including four geographically diverse academic medical centers, was queried to determine the use of diagnostic spirometry testing in African American children and young adults 5‐34 years of age with sickle cell disease (SCD) with or without a documented history of asthma and/or acute chest syndrome (ACS). A total of 2749 patients were identified with SCD, of these 577 had asthma and 409 had ACS. Cross‐referencing the CPT code for diagnostic spirometry showed that for patients identified as having SCD, a history of ACS, and a diagnosis of asthma, only 31% across all four centers had spirometry. Having an asthma diagnosis was associated with ACS. Among SCD patients with asthma, the proportion with ACS for the four centers was 47%, 75%, 38%, and 36% respectively. The bivariate association between asthma and ACS for each Center was significant for each (P < .001). To summarize, only one third of patients with co‐morbid SCD, ACS, and asthma received the spirometry procedure as recommended in evidence‐based guidelines, suggesting limited testing for changes in pulmonary function. Future studies to determine barriers and facilitators to implementation of pulmonary testing in SCD are warranted.
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    The OneFlorida Data Trust: a centralized, translational research data infrastructure of statewide scope
    (Oxford University Press, 2022) Hogan, William R.; Shenkman, Elizabeth A.; Robinson, Temple; Carasquillo, Olveen; Robinson, Patricia S.; Essner, Rebecca Z.; Bian, Jiang; Lipori, Gigi; Harle, Christopher; Magoc, Tanja; Manini, Lizabeth; Mendoza, Tona; White, Sonya; Loiacono, Alex; Hall, Jackie; Nelson, Dave; Biostatistics and Health Data Science, Richard M. Fairbanks School of Public Health
    The OneFlorida Data Trust is a centralized research patient data repository created and managed by the OneFlorida Clinical Research Consortium (“OneFlorida”). It comprises structured electronic health record (EHR), administrative claims, tumor registry, death, and other data on 17.2 million individuals who received healthcare in Florida between January 2012 and the present. Ten healthcare systems in Miami, Orlando, Tampa, Jacksonville, Tallahassee, Gainesville, and rural areas of Florida contribute EHR data, covering the major metropolitan regions in Florida. Deduplication of patients is accomplished via privacy-preserving entity resolution (precision 0.97–0.99, recall 0.75), thereby linking patients’ EHR, claims, and death data. Another unique feature is the establishment of mother-baby relationships via Florida vital statistics data. Research usage has been significant, including major studies launched in the National Patient-Centered Clinical Research Network (“PCORnet”), where OneFlorida is 1 of 9 clinical research networks. The Data Trust’s robust, centralized, statewide data are a valuable and relatively unique research resource.