Browsing by Author "Li, Yiping"

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    Contralateral Vasospasm in an Uncomplicated Elective Anterior Communicating Artery Aneurysm Clipping
    (Elsevier, 2020-06) Knight, James A.; Bigder, Mark G.; Brigido, Mauricio M.; Li, Yiping; Steinberg, Gary K.; School of Education
    Background Cerebral vasospasm following clipping of an unruptured aneurysm is a rare phenomenon. When it does occur, cerebral vasospasm usually occurs on the side ipsilateral to the surgical intervention. Case Description A 68-year-old man underwent right-sided pterional craniotomy for clipping of an unruptured anterior communicating artery aneurysm and experienced contralateral vasospasm 5 days later. Conclusions We further discuss the pathophysiology underlying vasospasm after uncomplicated craniotomy and nonhemorrhagic aneurysm clipping.
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    Surgical decompression in acute spinal cord injury: A review of clinical evidence, animal model studies, and potential future directions of investigation
    (Frontiers Media, 2014) Li, Yiping; Walker, Chandler L.; Zhang, Yi Ping; Shields, Christopher B.; Xu, Xiao-Ming; Neurological Surgery, School of Medicine
    The goal for treatment in acute spinal cord injury (SCI) is to reduce the extent of secondary damage and facilitate neurologic regeneration and functional recovery. Although multiple studies have investigated potential new therapies for the treatment of acute SCI, outcomes and management protocols aimed at ameliorating neurologic injury in patients remain ineffective. More recent clinical and basic science research have shown surgical interventions to be a potentially valuable modality for treatment; however, the role and timing of surgical decompression, in addition to the optimal surgical intervention, remain one of the most controversial topics pertaining to surgical treatment of acute SCI. As an increasing number of potential treatment modalities emerge, animal models are pivotal for investigating its clinical application and translation into human trials. This review critically appraises the available literature for both clinical and basic science studies to highlight the extent of investigation that has occurred, specific therapies considered, and potential areas for future research.